Evidence map›Paper›PMID 34502075›Full record

ReviewInternational journal of molecular sciences2021

(Dys)function Follows Form: Nucleic Acid Structure, Repeat Expansion, and Disease Pathology in

Xiaonan Zhao, Karen Usdin

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Emerging drivers of DNA repeat expansions.Biochemical Society transactions · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Impacts of Molecular Structure on Nucleic Acid-Protein Interactions.International journal of molecular sciences · 2022
    Article
  6. The remodeling of Z-DNA in the mammalian germ line.Biochemical Society transactions · 2022
    Article
  7. Review
  8. The polyG diseases: a new disease entity.Acta neuropathologica communications · 2022
    Review
  9. Review
  10. Mechanisms of theInternational journal of molecular sciences · 2022
    Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xiaonan ZhaoLaboratory of Cell and Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0001-7281-3914
Karen UsdinLaboratory of Cell and Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
National Institutes of Health · US

Funding

The pathology consequences of repeat expansion in the Repeat Expansion DiseasesZIADK057602 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI USDIN, KAREN P. · 2009 to 2025
$11.5M
NIDDK NIH HHS 1ZIADK057602
6 · The paper itself

Abstract

Fragile X-related disorders (FXDs), also known as

Indexed as

Trinucleotide Repeat ExpansionAnimalsFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeHumansFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1chromosome fragilityfragile X-associated primary ovarian insufficiency (FXPOI)fragile X-associated tremor/ataxia syndrome (FXTAS)fragile X syndrome (FXS)repeat-associated non-AUG (RAN) translationrepeat expansionrepeat instabilityrepeat-mediated gene silencingRNA gain-of-function

Identifiers

PMID34502075
PMCPMC8431139
OpenAlexW3196100886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.