Evidence map›Paper›PMID 34502028›Full record

ReviewInternational journal of molecular sciences2021

Targeted Delivery of Drugs and Genes Using Polymer Nanocarriers for Cancer Therapy.

Wentao Xia, Zixuan Tao, Bin Zhu, Wenxiang Zhang, Chang Liu, Siyu Chen, Mingming Song

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
7.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 149 citations in OpenAlex.

  1. Review
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  16. Enhanced Vitamin DPolymers · 2025
    Article
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  20. Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wentao XiaSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China.
Zixuan TaoSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China.
Bin ZhuSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China.
Wenxiang ZhangSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China.ORCID 0000-0002-1077-8014
Chang LiuSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China.ORCID 0000-0001-9251-708X
Siyu ChenSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China.ORCID 0000-0002-3809-1062
Mingming SongSchool of Life Science and Technology, China Pharmaceutical University, Nanjing 211198, China.ORCID 0000-0003-2140-9705
China Pharmaceutical University · CN

Funding

National Natural Science Foundation of China grant no. 31800992 to S.Y.C., 81800512 to W.X.Z., 92057112 and 31771298 to C.L.Natural Science Foundation of Jiangsu Province grant no. BK20180554 to S.Y.C., BK20180577 to W.X.Z.
6 · The paper itself

Abstract

Cancer is one of the primary causes of worldwide human deaths. Most cancer patients receive chemotherapy and radiotherapy, but these treatments are usually only partially efficacious and lead to a variety of serious side effects. Therefore, it is necessary to develop new therapeutic strategies. The emergence of nanotechnology has had a profound impact on general clinical treatment. The application of nanotechnology has facilitated the development of nano-drug delivery systems (NDDSs) that are highly tumor selective and allow for the slow release of active anticancer drugs. In recent years, vehicles such as liposomes, dendrimers and polymer nanomaterials have been considered promising carriers for tumor-specific drug delivery, reducing toxicity and improving biocompatibility. Among them, polymer nanoparticles (NPs) are one of the most innovative methods of non-invasive drug delivery. Here, we review the application of polymer NPs in drug delivery, gene therapy, and early diagnostics for cancer therapy.

Indexed as

Drug CarriersAnimalsAntineoplastic AgentsHumansNanoparticlesNeoplasmsPolymersAntineoplastic AgentsDrug CarriersPolymerscancer therapydrug deliverypolymer nanocarriers

Identifiers

PMID34502028
PMCPMC8431379
OpenAlexW3193291452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.