Evidence map›Paper›PMID 34501904›Full record

ArticleInternational journal of environmental research and public health2021

Implementation of Sample Pooling Procedure Using a Rapid SARS-CoV-2 Diagnostic Real-Time PCR Test Performed Prior to Hospital Admission of People with Intellectual Disabilities.

Antonino Musumeci, Mirella Vinci, Francesca L'Episcopo, Alda Ragalmuto, Vincenzo Neri, Michele Roccella, Giuseppe Quatrosi, Luigi Vetri, Francesco Calì

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Detection ofInsects · 2024
    Article
  2. Allelic Variations in the Human GenesInternational journal of molecular sciences · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonino MusumeciOasi Research Institute-IRCCS, Via Conte Ruggero 73, 94018 Troina, Italy.
Mirella VinciOasi Research Institute-IRCCS, Via Conte Ruggero 73, 94018 Troina, Italy.
Francesca L'EpiscopoOasi Research Institute-IRCCS, Via Conte Ruggero 73, 94018 Troina, Italy.ORCID 0000-0003-3292-9677
Alda RagalmutoOasi Research Institute-IRCCS, Via Conte Ruggero 73, 94018 Troina, Italy.ORCID 0000-0002-7399-964X
Vincenzo NeriOasi Research Institute-IRCCS, Via Conte Ruggero 73, 94018 Troina, Italy.
Michele RoccellaDepartment of Psychology, Educational Science and Human Movement, University of Palermo, 90128 Palermo, Italy.ORCID 0000-0002-7371-0228
Giuseppe QuatrosiDepartment of Sciences for Health Promotion and Mother and Child Care "G. D'Alessandro", University of Palermo, 90128 Palermo, Italy.
Luigi VetriOasi Research Institute-IRCCS, Via Conte Ruggero 73, 94018 Troina, Italy.ORCID 0000-0002-0121-3396
Francesco CalìOasi Research Institute-IRCCS, Via Conte Ruggero 73, 94018 Troina, Italy.ORCID 0000-0001-8667-8223

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reliability, accuracy, and timeliness of diagnostic testing for SARS-CoV-2 infection have allowed adequate public health management of the disease, thus notably helping the timely mapping of viral spread within the community. Furthermore, the most vulnerable populations, such as people with intellectual disability and dementia, represent a high-risk group across multiple dimensions, including a higher prevalence of pre-existing conditions, lower health maintenance, and a propensity for rapid community spread. This led to an urgent need for reliable in-house rapid testing to be performed prior to hospital admission. In the present study, we describe a pooling procedure in which oropharyngeal and nasopharyngeal swabs for SARS-CoV-2 detection (performed prior to hospital admission using rapid RT-PCR assay) are pooled together at the time of sample collection. Sample pooling (groups of 2-4 samples per tube) allowed us to significantly reduce response times, consumables, and personnel costs while maintaining the same test sensitivity.

Indexed as

COVID-19Intellectual DisabilityHospitalsHumansReal-Time Polymerase Chain ReactionReproducibility of ResultsSARS-CoV-2Sensitivity and Specificityhospital admissionRT-PCRsample poolingSARS-CoV-2sensitivity

Identifiers

PMID34501904
PMCPMC8431078

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.