ReviewInternational journal of environmental research and public health2021
Comorbid Insomnia and Obstructive Sleep Apnea (COMISA): Current Concepts of Patient Management.
Review in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06149273 (Treatment of Insomnia in Primary Care Study), which is not on this map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Treatment of Insomnia in Primary Care Study
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Trazodone changed the polysomnographic sleep architecture in insomnia disorder: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Daridorexant in severe obstructive sleep apnea: effects on sleep-disordered breathing and sleep.Sleep · 2026Trial
- A randomized, double-blind, placebo-controlled, crossover study of respiratory safety of lemborexant in moderate to severe obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Trial
- Effect of lemborexant on insomnia severity, morning alertness, and cognition in participants with insomnia disorder and mild obstructive sleep apnea.Sleep medicine: X · 2026Article
- Depressive and insomnia symptoms and incident dementia risk: A 12-year study in U.S. older adults.Journal of affective disorders · 2026Article
- Adherence to positive airway pressure therapy in patients with comorbid restless legs syndrome and obstructive sleep apnea: a retrospective cohort study.Sleep & breathing = Schlaf & Atmung · 2026Article
- Optimizing CPAP Adherence in Obstructive Sleep Apnea: A Narrative Review of Practical Strategies for Everyday Clinical Care.Healthcare (Basel, Switzerland) · 2026Review
- Obstructive Sleep Apnea: A Potential Sleeping Giant of Sport Performance and Health?Sports medicine (Auckland, N.Z.) · 2026Article
- Comorbid Insomnia and Sleep Apnea Mechanistic Convergence, Phenotypic Heterogeneity, and Clinical Implications.Current sleep medicine reports · 2026Article
- Insomnia, Sleep Apnea, and Incidence of Hypertension and Cardiovascular Disease Among Men and Women US Veterans.Journal of the American Heart Association · 2025Article
- "Characterization of Brazilian Dentistry in Dental Sleep Medicine".Sleep science (Sao Paulo, Brazil) · 2025Article
- Clinical phenotypes of obstructive sleep apnea in a sample of Saudi population.Sleep & breathing = Schlaf & Atmung · 2025Article
- Treatment choice in mild to moderate sleep apnoea in the European Sleep Apnea Database.ERJ open research · 2025Article
- Sleep Bruxism and Hypobaric Hypoxia Exposure: Exploring the Physiological Association.Journal of clinical medicine · 2025Review
- Comorbid Insomnia and Sleep Apnea Across the Pediatric Age: A Polysomnographic Study.Children (Basel, Switzerland) · 2025Article
- Paradoxical Insomnia Versus Atypical Obstructive Sleep Apnea or Mixed Disorder? Case Report and Literature Review.Clinical case reports · 2025Article
- Understanding the clinical management of co-occurring sleep-related bruxism and obstructive sleep apnea in adults: A narrative and critical review.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2025Review
- Biological pathways and mechanisms linking COPD and cardiovascular disease.Therapeutic advances in chronic disease · 2025Review
- Concentrated micro choice-based treatment for type 2 diabetes is associated with decreased risk of sleep apnoea, less daytime sleepiness and lower insomnia symptoms. A non-randomized pre - post pilot study.Frontiers in sleep · 2025Article
- Co-morbid Insomnia and Sleep Apnea (COMISA) in a large sample of Iranian: prevalence and associations in a sleep clinic population.Sleep & breathing = Schlaf & Atmung · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea (OSA) and insomnia are the two most common sleep disorders among the general population, and they may often coexist in patients with sleep-disordered breathing (SDB). The higher prevalence of insomnia symptoms in patients with OSA (40-60%) compared to that observed in the general population has thus led researchers to identify a new disorder named comorbid insomnia and OSA (COMISA), whose true burden has been so far largely underestimated. The combined treatment of COMISA patients with positive-airway pressure ventilation (PAP) with cognitive behavioral therapy for insomnia (CBT
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.