Evidence map›Paper›PMID 34501480›Full record

ArticleJournal of clinical medicine2021

Radioactive Iodine Treatment and the Risk of Long-Term Cardiovascular Morbidity and Mortality in Thyroid Cancer Patients: A Nationwide Cohort Study.

Chun-Hao Kao, Chi-Hsiang Chung, Wu-Chien Chien, Daniel Hueng-Yuan Shen, Li-Fan Lin, Chuang-Hsin Chiu, Cheng-Yi Cheng, Chien-An Sun, Ping-Ying Chang

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
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  4. Cardiovascular disease and radiopharmaceutical therapies- an underestimated risk?European journal of nuclear medicine and molecular imaging · 2025
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chun-Hao KaoDepartment of Nuclear Medicine, Tri-Service General Hospital and National Defense Medical Center, Taipei City 11490, Taiwan.ORCID 0000-0001-9239-7831
Chi-Hsiang ChungSchool of Public Health, National Defense Medical Center, Taipei City 11490, Taiwan.ORCID 0000-0002-4576-9900
Wu-Chien ChienSchool of Public Health, National Defense Medical Center, Taipei City 11490, Taiwan.ORCID 0000-0002-3286-0780
Daniel Hueng-Yuan ShenDepartment of Nuclear Medicine, Tri-Service General Hospital and National Defense Medical Center, Taipei City 11490, Taiwan.
Li-Fan LinDepartment of Nuclear Medicine, Tri-Service General Hospital and National Defense Medical Center, Taipei City 11490, Taiwan.ORCID 0000-0002-5583-2993
Chuang-Hsin ChiuDepartment of Nuclear Medicine, Tri-Service General Hospital and National Defense Medical Center, Taipei City 11490, Taiwan.ORCID 0000-0002-7275-6558
Cheng-Yi ChengDepartment of Nuclear Medicine, Tri-Service General Hospital and National Defense Medical Center, Taipei City 11490, Taiwan.
Chien-An SunDepartment of Public Health, College of Medicine, Fu-Jen Catholic University, New Taipei City 24205, Taiwan.ORCID 0000-0001-9041-0537
Ping-Ying ChangDivision of Hematology/Oncology, Department of Internal Medicine, Tri-Service General Hospital and National Defense Medical Center, Taipei City 11490, Taiwan.
Tri-Service General Hospital · TWFu Jen Catholic University · TW

Funding

Tri-Service General Hospital TSGH-B-109010Tri-Service General Hospital TSGH-B-110012
6 · The paper itself

Abstract

(1) Background: This study aimed to investigate the association between radioactive iodine (RAI) and long-term cardiovascular disease (CVD) morbidity/mortality in thyroid cancer. (2) Methods: The study was conducted using data from the Taiwan National Health Insurance Database during 2000-2015. Thyroid cancer patients aged ≥20 years were categorized into RAI (thyroidectomy with RAI) and non-RAI (thyroidectomy only) groups. The Cox proportional hazard regression model and Kaplan-Meier method were used for analysis. (3) Results: A total of 13,310 patients were included. Kaplan-Meier analysis demonstrated that the two groups had similar cumulative risks of CVD (log-rank

Indexed as

cardiovascularcomorbiditymortalityradioactive iodinethyroid cancer

Identifiers

PMID34501480
PMCPMC8432460
OpenAlexW3196386380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.