Evidence map›Paper›PMID 34501453›Full record

ArticleJournal of clinical medicine2021

Analysis of Patient Factors Affecting In Vitro Characteristics of Subacromial Bursal Connective Tissue Progenitor Cells during Rotator Cuff Repair.

Daichi Morikawa, Benjamin C Hawthorne, Mary Beth R McCarthy, Nicholas Bellas, Jeremiah D Johnson, Maxwell T Trudeau, Kyle V Murphy, Michael R Mancini, Matthew R LeVasseur, Mark P Cote and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Rotator cuff tears.Nature reviews. Disease primers · 2024
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Daichi MorikawaDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Benjamin C HawthorneDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Mary Beth R McCarthyDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Nicholas BellasDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Jeremiah D JohnsonDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Maxwell T TrudeauDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.ORCID 0000-0002-5936-6782
Kyle V MurphyDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Michael R ManciniDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Matthew R LeVasseurDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Mark P CoteDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
Augustus D MazzoccaDepartment of Orthopaedic Surgery, University of Connecticut, Farmington, CT 06032, USA.
University of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unsatisfactory failure rates following rotator cuff (RC) repair have led orthopaedic surgeons to explore biological augmentation of the healing enthesis. The subacromial bursa (SB) contains abundant connective tissue progenitor cells (CTPs) that may aid in this process. The purpose of the study was to investigate the influence of patient demographics and tear characteristics on the number of colony-forming units (CFUs) and nucleated cell count (NCC) of SB-derived CTPs. In this study, we harvested SB tissue over the supraspinatus tendon and muscle in 19 patients during arthroscopic RC repair. NCC of each sample was analyzed on the day of the procedure. After 14 days, CFUs were evaluated under a microscope. Spearman's rank correlation coefficient was then used to determine the relationship between CFUs or NCC and patient demographics or tear characteristics. The study found no significant correlation between patient demographics and the number of CFUs or NCC of CTPs derived from the SB (

Indexed as

connective tissue progenitorsmesenchymal stem cellsrotator cuffshouldersubacromial bursa

Identifiers

PMID34501453
PMCPMC8432549
OpenAlexW3198054199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.