Evidence map›Paper›PMID 34501432›Full record

ArticleJournal of clinical medicine2021

Foot Revascularization Avoids Major Amputation in Persons with Diabetes and Ischaemic Foot Ulcers.

Marco Meloni, Daniele Morosetti, Laura Giurato, Matteo Stefanini, Giorgio Loreni, Marco Doddi, Andrea Panunzi, Alfonso Bellia, Roberto Gandini, Enrico Brocco and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
  5. Observational
  6. Article
  7. [Research on the pathogenesis and treatment of diabetic foot ulcer wounds].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Emerging technologies for the management of diabetic foot ulceration: a review.Frontiers in clinical diabetes and healthcare · 2024
    Review
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Marco MeloniDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-3789-9622
Daniele MorosettiDepartment of Interventional Radiology, University of Rome "Tor Vergata", 00133 Rome, Italy.
Laura GiuratoDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Matteo StefaniniDepartment of Radiology, Casilino Polyclinic, 00169 Rome, Italy.ORCID 0000-0001-5485-1546
Giorgio LoreniDepartment of Interventional Radiology, Sandro Pertini Hospital, 00157 Rome, Italy.
Marco DoddiDepartment of Interventional Radiology, Sandro Pertini Hospital, 00157 Rome, Italy.
Andrea PanunziDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Alfonso BelliaDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Roberto GandiniDepartment of Interventional Radiology, University of Rome "Tor Vergata", 00133 Rome, Italy.
Enrico BroccoDiabetic Foot Centre, Abano Terme Polyclinic, 35031 Abano Terme, Italy.ORCID 0000-0002-9008-4687
José Luis Lazaro-MartinezInstituto de Investigacion Sanitaria San Carlo Hospital, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0001-6110-0265
Davide LauroDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-8597-4415
Luigi UccioliDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0001-5087-2091
University of Rome Tor Vergata · ITOspedale Sandro Pertini · ITPoliclinico Abano Terme · ITPoliclinico Casilino · ITUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aims to evaluate the effectiveness of foot revascularization in persons with diabetic foot ulcers (DFUs) and below-the-ankle (BTA) arterial disease. Consecutive patients referred for a new active ischaemic DFU requiring lower limb revascularization were considered. Among those, only patients with a BTA arterial disease were included. Revascularization procedures were retrospectively analysed: in the case of successful foot revascularization (recanalization of pedal artery, or plantar arteries or both) or not, patients were respectively divided in two groups, successful foot perfusion (SFP) and failed foot perfusion (FFP). Healing, minor and major amputation at 12 months of follow-up were evaluated and compared. Eighty patients (80) were included. The mean age was 70.5 ± 10.9 years, 55 (68.7%) were male, 72 (90%) were affected by type 2 diabetes with a mean duration of 22.7 ± 11.3 years. Overall 45 (56.2%) patients healed, 47 (58.7%) had minor amputation and 13 (16.2%) major amputation. Outcomes for SFP and FFP were respectively: healing (89.3 vs. 9.1%,

Indexed as

critical limb ischaemiadiabetesdiabetic foot ulcerrevascularizationwound healing

Identifiers

PMID34501432
PMCPMC8432560
OpenAlexW3198442192

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.