Evidence map›Paper›PMID 34501424›Full record

ArticleJournal of clinical medicine2021

The Prognosis of Baseline Mitral Regurgitation in Patients with Transcatheter Aortic Valve Implantation.

Juqian Zhang, Arnaud Bisson, Jad Boumhidi, Julien Herbert, Christophe Saint Etienne, Anne Bernard, Gregory Y H Lip, Laurent Fauchier

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Balloon aortic valvuloplasty for severe aortic stenosis may reduce mitral regurgitation in mid-term follow-up.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Juqian ZhangLiverpool Centre for Cardiovascular Science, Liverpool Heart and Chest Hospital, University of Liverpool, Liverpool L69 7ZX, UK.ORCID 0000-0002-9653-8635
Arnaud BissonService de Cardiologie, Centre Hospitalier Universitaire et Faculté de Médecine, Université de Tours, CEDEX 1, 37044 Tours, France.ORCID 0000-0002-3449-1800
Jad BoumhidiService de Cardiologie, Centre Hospitalier Universitaire et Faculté de Médecine, Université de Tours, CEDEX 1, 37044 Tours, France.
Julien HerbertService de Cardiologie, Centre Hospitalier Universitaire et Faculté de Médecine, Université de Tours, CEDEX 1, 37044 Tours, France.
Christophe Saint EtienneService de Cardiologie, Centre Hospitalier Universitaire et Faculté de Médecine, Université de Tours, CEDEX 1, 37044 Tours, France.
Anne BernardService de Cardiologie, Centre Hospitalier Universitaire et Faculté de Médecine, Université de Tours, CEDEX 1, 37044 Tours, France.ORCID 0000-0003-4470-8222
Gregory Y H LipLiverpool Centre for Cardiovascular Science, Liverpool Heart and Chest Hospital, University of Liverpool, Liverpool L69 7ZX, UK.ORCID 0000-0002-7566-1626
Laurent FauchierService de Cardiologie, Centre Hospitalier Universitaire et Faculté de Médecine, Université de Tours, CEDEX 1, 37044 Tours, France.ORCID 0000-0002-9267-1658
Université de Tours · FRUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitral regurgitation (MR) is the most common valvular lesion in transcatheter aortic valve implantation (TAVI) recipients. This study aims to assess the long-term prognostic impact of baseline MR in TAVI patients.

methodsAdult patients who underwent TAVI were identified in the French National Hospital Discharge Database. All-cause and cardiovascular mortality, stroke, and rehospitalization with heart failure (HF) were compared in TAVI patients with and without baseline MR and tricuspid regurgitation (TR), respectively; the associations of MR and TR with the outcomes were assessed by Cox regression.

resultsBaseline MR was identified in 8240 TAVI patients. Patients with baseline MR have higher yearly incidence of all-cause mortality (HR: 1.192, 95% confidence interval CI: 1.125-1.263), cardiovascular mortality (HR: 1.313, 95%CI: 1.210-1.425), and rehospitalization for heart failure (HF) (HR: 1.411, 95%CI: 1.340-1.486) compared to those without, except for stroke rate (HR: 0.988, 95%CI: 0.868-1.124). Neither baseline MR nor TR was an independent risk predictor for all-cause mortality or cardiovascular mortality in TAVI patients. Baseline MR was independently associated with rehospitalization for HF in TAVI patients.

conclusionsBaseline MR and TR were associated with increased all-cause and cardiovascular mortality post-TAVI, however, neither of them was independent predictor for all-cause or cardiovascular mortality.

Indexed as

all-cause mortalitycardiovascular mortalitymitral regurgitationtranscatheter aortic valve implantationtricuspid regurgitation

Identifiers

PMID34501424
PMCPMC8432060
OpenAlexW3198326297

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.