Evidence map›Paper›PMID 34501396›Full record

ArticleJournal of clinical medicine2021

Adiposity Is Related to Inflammatory Disease Activity in Juvenile Idiopathic Arthritis.

Gisela Diaz-Cordovés Rego, Esmeralda Núñez-Cuadros, Natalia Mena-Vázquez, Soledad Aguado Henche, Rocío Galindo-Zavala, Sara Manrique-Arija, Laura Martín-Pedraz, Rocio Redondo-Rodríguez, Francisco Javier Godoy-Navarrete, Antonio Fernández-Nebro

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Gisela Diaz-Cordovés RegoInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Málaga, Spain.
Esmeralda Núñez-CuadrosUGC de Pediatría, Hospital Regional Universitario de Málaga, 29009 Málaga, Spain.
Natalia Mena-VázquezInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Málaga, Spain.ORCID 0000-0001-6173-2051
Soledad Aguado HencheDepartamento de Anatomía y Embriología Humana, Facultad de Medicina, Universidad de Alcalá de Henares, 29009 Madrid, Spain.
Rocío Galindo-ZavalaUGC de Pediatría, Hospital Regional Universitario de Málaga, 29009 Málaga, Spain.
Sara Manrique-ArijaInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Málaga, Spain.ORCID 0000-0003-2284-7846
Laura Martín-PedrazUGC de Pediatría, Hospital Regional Universitario de Málaga, 29009 Málaga, Spain.
Rocio Redondo-RodríguezInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Málaga, Spain.
Francisco Javier Godoy-NavarreteInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Málaga, Spain.
Antonio Fernández-NebroInstituto de Investigación Biomédica de Málaga (IBIMA), 29010 Málaga, Spain.ORCID 0000-0002-2962-9844
Hospital Regional Universitario de Málaga · ESUniversidad de Alcalá · ES

Funding

Sociedad Española de Reumatología Pediatrica Grant for medical researchers of the "Sociedad Española de Reumatología Pediatrica"
6 · The paper itself

Abstract

objectiveTo identify factors associated with the higher proportion of fatty tissue and overweight/obesity observed in patients with juvenile idiopathic arthritis (JIA). PATIENTS AND

methodsWe performed a cross-sectional study of 80 JIA patients aged 4-15 years with 80 age- and sex-matched healthy controls. Body composition was assessed using dual-energy x-ray absorptiometry. The 27-joint Juvenile Arthritis Disease Activity score (JADAS27) was calculated. Two multivariate models were constructed to identify factors associated with overweight/obesity and fat mass index (FMI).

resultsNo differences were found between cases and controls in body mass index (BMI) or body composition. However, compared with controls, patients with a high inflammatory activity (JADAS27 > 4.2 for oligoarticular JIA or >8.5 for polyarticular disease) had higher values for BMI (

conclusionOur study revealed no differences between JIA patients with well-controlled disease and low disability and the healthy population in BMI or body composition. Furthermore, the association observed between inflammatory activity and adiposity could be responsible for poorer clinical course.

Indexed as

adiposityinflammatory disease activityjuvenile idiopathic arthritis

Identifiers

PMID34501396
PMCPMC8432058
OpenAlexW3196497522

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.