ArticleJournal of clinical medicine2021
Achalasia in Children-Clinical Presentation, Diagnosis, Long-Term Treatment Outcomes, and Quality of Life.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Dietary management and feeding considerations of pediatric aerodigestive and upper gastrointestinal motility disorders.Journal of pediatric gastroenterology and nutrition · 2026Guideline
- Outcome reporting in studies of paediatric achalasia: A systematic review.Journal of pediatric gastroenterology and nutrition · 2025Pooled it
- Beyond Mechanical Failure: Esophagitis Causing Post Myotomy Obstruction in Congenital Achalasia.Oman medical journal · 2026Article
- Clinical characteristics and treatment outcomes of pediatric achalasia: a 10-year experience from a tertiary center in Iran.BMC research notes · 2025Article
- Peroral endoscopic myotomy in children with achalasia: A review of the literature.World journal of gastrointestinal endoscopy · 2025Review
- Efficacy of esophageal balloon dilatation with Botox injection in children with achalasia referred to a tertiary care center.Scientific reports · 2025Article
- Article
- Review
- Peroral Endoscopic Myotomy for Pediatric Achalasia: A Retrospective Analysis of 21 Cases With a Minimum Follow-Up of 5 Years.Frontiers in pediatrics · 2022Article
- Esophageal Dysphagia in Children: State of the Art and Proposal for a Symptom-Based Diagnostic Approach.Frontiers in pediatrics · 2022Review
- Quality-of-life Assessment among Children with Esophageal Achalasia.Journal of Indian Association of Pediatric SurgeonsArticle
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn spite of the introduction of peroral endoscopic myotomy (POEM), Heller myotomy (HM) remains the mainstay of treatment and the role of pneumatic dilatation (PD) is being debated. The aim of this study was to present a single-center experience in the diagnostic approach and treatment of esophageal achalasia (EA), including the long-term assessment of the QoL.
methodsData collection was based on the retrospective analysis of clinical notes and prospective interviews with patients and their parents.
resultsThe study group consisted of 60 patients with EA (F: 26, M: 34), with a median age of 12.0 (1-17) years at diagnosis. The time from the first symptoms until the diagnosis was 1.0 year (0.5-2.0) and the most common were: regurgitation (91.3%), dysphagia (84.8%), and chest pain (47.8%). The diagnostic approach showed a high sensitivity for barium X-ray follow through, esophageal manometry, and endoscopy. Overall, a long-term good outcome of HM was achieved in 27 out of 37 patients (73%) and it was negatively affected by the time between the first symptoms and the diagnosis. Out of the 16 patients who underwent PD before HM, a good outcome was achieved in 14 patients (87.5%), compared to 13 out of 21 patients (62%) who only underwent HM (
conclusionsPatients suspected of EA should undergo a thorough clinical evaluation including a manometry, a barium X-ray, and an endoscopy. HM is a safe and effective treatment for achalasia and the outcome is not worsened by a preceding endoscopic PD. In most patients, HM alleviates symptoms, although an impaired QoL is common in long-term follow ups.
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