Evidence map›Paper›PMID 34501344›Full record

ArticleJournal of clinical medicine2021

Erythema Increase Predicts Psoriasis Improvement after Phototherapy.

Trinidad Montero-Vilchez, Antonio Martinez-Lopez, Alvaro Sierra-Sanchez, Miguel Soler-Gongora, Eladio Jimenez-Mejias, Alejandro Molina-Leyva, Agustin Buendia-Eisman, Salvador Arias-Santiago

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Analysis of the modification of skin and gut microbiota in psoriasis patients treated with phototherapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  3. Epidermal Junctions and Skin Inflammation.Journal of clinical medicine · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Trinidad Montero-VilchezDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.
Antonio Martinez-LopezDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.
Alvaro Sierra-SanchezInstituto de Investigación Biosanitaria GRANADA, 18012 Granada, Spain.ORCID 0000-0003-4511-408X
Miguel Soler-GongoraDermatology Department, Faculty of Medicine, University of Granada, 18001 Granada, Spain.
Eladio Jimenez-MejiasEpidemiology and Public Health Department, Faculty of Medicine, University of Granada, 18012 Granada, Spain.
Alejandro Molina-LeyvaDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.ORCID 0000-0001-6882-2113
Agustin Buendia-EismanDermatology Department, Faculty of Medicine, University of Granada, 18001 Granada, Spain.
Salvador Arias-SantiagoDermatology Department, Hospital Universitario Virgen de las Nieves, Avenida de Madrid, 15, 18012 Granada, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a major global health problem. There is a need to develop techniques to help physicians select the most appropriate cost-effective therapy for each patient. The main objectives of this study are (1) to evaluate changes in epidermal barrier function and skin homeostasis after phototherapy and (2) to explore potentially predictive values in epidermal barrier function and skin homeostasis to assess clinical improvement after fifteen sessions of phototherapy. A total of 76 subjects, 38 patients with plaque-type psoriasis and 38 gender- and age-matched healthy volunteers, were included in the study. Erythema, transepidermal water loss (TEWL), temperature, stratum corneum hydration (SCH), pH, sebum, and antioxidant capacity were measured before and after the first and fifteenth phototherapy session. Erythema (401.09 vs. 291.12 vs. 284.52 AU,

Indexed as

phototherapypsoriasisskin barrierskin homeostasisskin physiology

Identifiers

PMID34501344
PMCPMC8432224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.