Evidence map›Paper›PMID 34501247›Full record

ArticleJournal of clinical medicine2021

Beneficial Effect of Successful Simultaneous Pancreas-Kidney Transplantation on Plasma Profile of Metalloproteinases in Type 1 Diabetes Mellitus Patients.

Jerzy Chudek, Aureliusz Kolonko, Jacek Ziaja, Tomasz Francuz, Dorota Kamińska, Aleksander J Owczarek, Piotr Kuczera, Agata Kujawa-Szewieczek, Mariusz Kusztal, Adrian P Kowalik and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Jerzy ChudekDepartment of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, 40-027 Katowice, Poland.ORCID 0000-0002-6367-7794
Aureliusz KolonkoDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, 40-027 Katowice, Poland.ORCID 0000-0002-9647-1872
Jacek ZiajaDepartment of General, Vascular and Transplant Surgery, Medical University of Silesia, 40-027 Katowice, Poland.
Tomasz FrancuzDepartment of Biochemistry, Medical University of Silesia, 40-752 Katowice, Poland.ORCID 0000-0002-6321-6090
Dorota KamińskaDepartment of Nephrology and Transplantation Medicine, Wrocław Medical University, 50-556 Wrocław, Poland.ORCID 0000-0003-2400-9328
Aleksander J OwczarekHealth Promotion and Obesity Management Unit, Department of Pathophysiology, Medical University of Silesia, 40-752 Katowice, Poland.ORCID 0000-0003-1179-6932
Piotr KuczeraDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, 40-027 Katowice, Poland.
Agata Kujawa-SzewieczekDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, 40-027 Katowice, Poland.
Mariusz KusztalDepartment of Nephrology and Transplantation Medicine, Wrocław Medical University, 50-556 Wrocław, Poland.ORCID 0000-0002-6502-0374
Adrian P KowalikDepartment of General, Vascular and Transplant Surgery, Medical University of Silesia, 40-027 Katowice, Poland.
Dominika Bożek-PająkDepartment of General, Vascular and Transplant Surgery, Medical University of Silesia, 40-027 Katowice, Poland.
Joanna KluzDepartment of Angiology, Hypertension and Diabetology, University Clinical Hospital, 50-556 Wrocław, Poland.
Piotr ChoręzaHealth Promotion and Obesity Management Unit, Department of Pathophysiology, Medical University of Silesia, 40-752 Katowice, Poland.
Robert KrólDepartment of General, Vascular and Transplant Surgery, Medical University of Silesia, 40-027 Katowice, Poland.
Magdalena KrajewskaDepartment of Nephrology and Transplantation Medicine, Wrocław Medical University, 50-556 Wrocław, Poland.
Lech CierpkaDepartment of General, Vascular and Transplant Surgery, Medical University of Silesia, 40-027 Katowice, Poland.
Andrzej WięcekDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, 40-027 Katowice, Poland.
Medical University of Silesia · PLWroclaw Medical University · PL

Funding

Narodowym Centrum Nauki 2013/09/B/NZ5/00258
6 · The paper itself

Abstract

It is not fully elucidated whether the restoring of normal glucose metabolism after successful simultaneous pancreas-kidney transplantation (SPK) improves vascular wall morphology and function in type 1 diabetic (T1D) patients. Therefore, we compared arterial stiffness, assessed by pulse wave velocity (PWV), carotid intima-media thickness (IMT), and biomarkers of arterial wall calcification in T1D patients after SPK or kidney transplantation alone (KTA). In 39 SPK and 39 KTA adult patients of similar age, PWV, IMT, circulating matrix metalloproteinases (MMPs) and calcification biomarkers were assessed at median 83 months post transplantation. Additionally, carotid plaques were visualized and semi-qualitatively classified. Although PWV and IMT values were similar, the occurrence of atherosclerotic plaques (51.3 vs. 70.3%,

Indexed as

arterial stiffnessatherosclerosisintima-media thicknessmatrix metalloproteinasessimultaneous pancreas kidney transplantationtype 1 diabetes

Identifiers

PMID34501247
PMCPMC8432100
OpenAlexW3196139897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.