Evidence map›Paper›PMID 34501216›Full record

ArticleJournal of clinical medicine2021

Sex Differences in the Clinical Features and Outcomes of Patients with Acute Coronary Syndrome Treated with Two Generations (Absorb and Magmaris) of Bioresorbable Vascular Scaffolds.

Adrian Włodarczak, Piotr Rola, Marek Szudrowicz, Magdalena Łanocha, Mateusz Barycki, Jan Jakub Kulczycki, Alicja Gosiewska, Karol Turkiewicz, Maciej Lesiak, Adrian Doroszko

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adrian WłodarczakDepartment of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland.ORCID 0000-0003-3104-7728
Piotr RolaDepartment of Cardiology, Provincial Specialized Hospital in Legnica, Iwaszkiewicza Str. 5, 59-220 Legnica, Poland.ORCID 0000-0002-0963-2712
Marek SzudrowiczDepartment of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland.
Magdalena ŁanochaAdalbert's Hospital, 61-144 Poznan, Poland.
Mateusz BaryckiDepartment of Cardiology, Provincial Specialized Hospital in Legnica, Iwaszkiewicza Str. 5, 59-220 Legnica, Poland.
Jan Jakub KulczyckiDepartment of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland.ORCID 0000-0002-6670-6044
Alicja GosiewskaFaculty of Mathematics and Information Science, Warsaw University of Technology, 00-662 Warsaw, Poland.ORCID 0000-0001-6563-5742
Karol TurkiewiczDepartment of Cardiology, The Copper Health Centre (MCZ), 59-300 Lubin, Poland.
Maciej Lesiak1st Department of Cardiology, Poznan University of Medical Sciences, 61-491 Poznan, Poland.
Adrian DoroszkoDepartment of Internal Medicine, Hypertension and Clinical Oncology, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0001-5472-028X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the developments in percutaneous coronary interventions (PCI), women are still more likely than men to have unfavorable outcomes after PCI performed in Acute Coronary Syndrome (ACS). The mechanisms of this phenomena are not fully understood. Potential benefits of bioresorbable scaffolds (BRS) may be particularly expressed in the female population. Nevertheless, the data available currently are inconsistent and limited. This study evaluated the gender-related differences in the short-term clinical outcomes in ACS patients treated with implantation of two generations of BRS (first generation, Absorb; second generation, Magmaris).

methodsThe study was divided into two arms. To the first one, we qualified 160 patients with ACS treated with PCI who received 210 Absorb scaffolds. The second arm was composed of 193 patients with ACS who underwent PCI with Magmaris implantation.

resultsThere were no significant sex-related differences in primary endpoints (cardiovascular-death, myocardial infarction, in-stent thrombosis) or principal secondary endpoints (of target-lesion failure, scaffold restenosis, death from any reason, other cardiovascular events) in either generation of BRS in a 1-year follow-up.

conclusionsBoth genders tended to have a similar outcome in routine clinical practice following BRS implantation due to ACS. The magnesium bioresorbable scaffold (Magmaris) early outcome seemed to be more favorable in comparison to the Absorb scaffold.

Indexed as

Absorbacute coronary syndrome (ACS)bioresorbable scaffold (BRS)coronary artery disease (CAD)gender-related prognosisMagmarispercutaneous coronary intervention (PCI)sex differences

Identifiers

PMID34501216
PMCPMC8432059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.