Evidence map›Paper›PMID 34500857›Full record

SynthesisMolecules (Basel, Switzerland)2021

Tualang Honey: A Decade of Neurological Research.

Khairunnuur Fairuz Azman, Che Badariah Abd Aziz, Rahimah Zakaria, Asma Hayati Ahmad, Nazlahshaniza Shafin, Che Aishah Nazariah Ismail

Abstract readSystematic Review
In one paragraph

Synthesis in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Honey on brain health: A promising brain booster.Frontiers in aging neuroscience · 2022
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khairunnuur Fairuz AzmanDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian 16150, Malaysia.ORCID 0000-0003-2735-0177
Che Badariah Abd AzizDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian 16150, Malaysia.
Rahimah ZakariaDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian 16150, Malaysia.ORCID 0000-0002-2459-3213
Asma Hayati AhmadDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian 16150, Malaysia.
Nazlahshaniza ShafinDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian 16150, Malaysia.ORCID 0000-0002-8524-1852
Che Aishah Nazariah IsmailDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia Health Campus, Kubang Kerian 16150, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tualang honey has been shown to protect against neurodegeneration, leading to improved memory/learning as well as mood. In addition, studies have also demonstrated its anti-inflammatory and antioxidant properties. However, a substantial part of this research lacks systematization, and there seems to be a tendency to start anew with every study. This review presents a decade of research on Tualang honey with a particular interest in the underlying mechanisms related to its effects on the central nervous system. A total of 28 original articles published between 2011 and 2020 addressing the central nervous system (CNS) effects of Tualang honey were analysed. We identified five main categories, namely nootropic, antinociceptive, stress-relieving, antidepressant, and anxiolytic effects of Tualang honey, and proposed the underlying mechanisms. The findings from this review may potentially be beneficial towards developing new therapeutic roles for Tualang honey and help in determining how best to benefit from this brain supplement.

Indexed as

AnimalsAnti-Anxiety AgentsAntidepressive AgentsAnti-Inflammatory AgentsAntioxidantsDietary SupplementsHoneyHumansMolecular StructurePhenolsProtective AgentsAnti-Anxiety AgentsAntidepressive AgentsAnti-Inflammatory AgentsAntioxidantsPhenolsProtective AgentsantidepressionantinociceptiveantioxidantsanxiolyticsnootropicsTualang honey

Identifiers

PMID34500857
PMCPMC8434576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.