Evidence map›Paper›PMID 34500810›Full record

ReviewMolecules (Basel, Switzerland)2021

Plant Flavonoids: Chemical Characteristics and Biological Activity.

Maria Celeste Dias, Diana C G A Pinto, Artur M S Silva

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 548 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
548citing papers in PubMed, 2 pooled it
65.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

548 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1,337 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Functionalization of Flavonoids with Lipases.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. A comprehensive review ofRSC advances · 2026
    Review
  19. Article
  20. Article

488 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maria Celeste DiasCentre for Functional Ecology, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal.ORCID 0000-0002-3083-6218
Diana C G A PintoLAQV/REQUIMTE, Department of Chemistry, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-4249-7089
Artur M S SilvaLAQV/REQUIMTE, Department of Chemistry, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-2861-8286
Rede de Química e Tecnologia · PT

Funding

Fundação para a Ciência e a Tecnologia SFRH/BPD/100865/2014
6 · The paper itself

Abstract

In recent years, more attention has been paid to natural sources of antioxidants. Flavonoids are natural substances synthesized in several parts of plants that exhibit a high antioxidant capacity. They are a large family, presenting several classes based on their basic structure. Flavonoids have the ability to control the accumulation of reactive oxygen species (ROS) via scavenger ROS when they are formed. Therefore, these antioxidant compounds have an important role in plant stress tolerance and a high relevance in human health, mainly due to their anti-inflammatory and antimicrobial properties. In addition, flavonoids have several applications in the food industry as preservatives, pigments, and antioxidants, as well as in other industries such as cosmetics and pharmaceuticals. However, flavonoids application for industrial purposes implies extraction processes with high purity and quality. Several methodologies have been developed aimed at increasing flavonoid extraction yield and being environmentally friendly. This review presents the most abundant natural flavonoids, their structure and chemical characteristics, extraction methods, and biological activity.

Indexed as

AnimalsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsFlavonoidsGreen Chemistry TechnologyHumansPhytochemicalsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsFlavonoidsPhytochemicalsantioxidantsbioactive compoundsextraction methodsnatural sourcesstructure

Identifiers

PMID34500810
PMCPMC8434187
OpenAlexW3198669059

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.