Evidence map›Paper›PMID 34500787›Full record

ArticleMolecules (Basel, Switzerland)2021

Contribution of the Adenosine 2A Receptor to Behavioral Effects of Tetrahydrocannabinol, Cannabidiol and PECS-101.

Todd M Stollenwerk, Samantha Pollock, Cecilia J Hillard

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Involvement of Adenosine ABrain and behavior · 2026
    Article
  3. Article
  4. Cannabidiol negatively modulates adenosine AActa neuropsychiatrica · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Todd M StollenwerkDepartment of Pharmacology and Toxicology and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0002-8847-7406
Samantha PollockDepartment of Pharmacology and Toxicology and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Cecilia J HillardDepartment of Pharmacology and Toxicology and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0002-9678-748X
Medical College of Wisconsin · US

Funding

Medical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7M
Cannabinoid-mediated mitigation of graft versus host disease: Roles of CB2 receptors and adenosine signalingR01HL139008 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI DROBYSKI, WILLIAM R., HILLARD, CECILIA J · 2017 to 2020
$2.2M
NHLBI NIH HHS R01 HL139008NIGMS NIH HHS GM080202NIGMS NIH HHS T32 GM080202Phytecs, Inc None
6 · The paper itself

Abstract

The cannabis-derived molecules, ∆

Indexed as

AnimalsCannabidiolDronabinolExploratory BehaviorInjections, IntraperitonealMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicReceptor, Adenosine A2ACannabidiolDronabinolReceptor, Adenosine A2A4′-fluoro-cannabidiolcannabinoid tetradcatalepsyelevated plus mazeequilibrative nucleoside transporterHUF-101marble bury

Identifiers

PMID34500787
PMCPMC8434367
OpenAlexW3196291008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.