Evidence map›Paper›PMID 34500785›Full record

ArticleMolecules (Basel, Switzerland)2021

An Evaluation of Understudied Phytocannabinoids and Their Effects in Two Neuronal Models.

Alex Straiker, Sierra Wilson, Wesley Corey, Michaela Dvorakova, Taryn Bosquez, Joye Tracey, Caroline Wilkowski, Kathleen Ho, Jim Wager-Miller, Ken Mackie

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Side-Chain Homologs of ΔMolecular neurobiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Alex StraikerGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.
Sierra WilsonGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.
Wesley CoreyGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.
Michaela DvorakovaGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0003-3002-8568
Taryn BosquezGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0002-0855-9672
Joye TraceyGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.
Caroline WilkowskiGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0002-3937-9746
Kathleen HoGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.ORCID 0000-0003-3751-3160
Jim Wager-MillerGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.
Ken MackieGill Center for Molecular Bioscience, Program in Neuroscience, Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN 47405, USA.
Indiana University Bloomington · US

Funding

Modulation of pain mechanisms by cannabis-derived phytochemicals.R01AT011162 · NCCIH · QUEEN'S MEDICAL CENTER · PI MACKIE, KENNETH, PENNER, REINHOLD · 2021 to 2025
$3.2M
INTEGRATIVE PREDOCTORAL TRAINING IN DRUG ABUSE RESEARCH AT INDIANA UNIVERSITYT32DA024628 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI Andrea Grace Hohmann, Kenneth Mackie · 2008 to 2026
$3.1M
NCCIH NIH HHS R01 AT011162NIDA NIH HHS T32 DA024628NIH HHS AT011162
6 · The paper itself

Abstract

Cannabis contains more than 100 phytocannabinoids. Most of these remain poorly characterized, particularly in neurons. We tested a panel of five phytocannabinoids-cannabichromene (CBC), cannabidiolic acid (CBDA), cannabidivarin (CBDV), cannabidivarinic acid (CBDVA), and Δ

Indexed as

Models, BiologicalAnimalsCannabinoidsCells, CulturedHumansMiceNeuronsPhytochemicalsCannabinoidsPhytochemicalscannabichromenecannabidiolic acidcannabidivarincannabidivarinic acidphytocannabinoidstetrahydrocannabivarin

Identifiers

PMID34500785
PMCPMC8434068
OpenAlexW3197972434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.