Evidence map›Paper›PMID 34500758›Full record

ReviewMolecules (Basel, Switzerland)2021

Chemo-Preventive Action of Resveratrol: Suppression of p53-A Molecular Targeting Approach.

Rokeya Akter, Md Habibur Rahman, Deepak Kaushik, Vineet Mittal, Diana Uivarosan, Aurelia Cristina Nechifor, Tapan Behl, Chenmala Karthika, Manuela Stoicescu, Mihai Alexandru Munteanu and 2 more

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rokeya AkterDepartment of Pharmacy, Jagannath University, Sadarghat, Dhaka 1100, Bangladesh.
Md Habibur RahmanDepartment of Global Medical Science, Yonsei University Wonju College of Medicine, Yonsei University, Wonju 26426, Korea.ORCID 0000-0001-6099-5693
Deepak KaushikDepartment of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001, India.ORCID 0000-0002-3286-196X
Vineet MittalDepartment of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001, India.ORCID 0000-0002-0980-5628
Diana UivarosanDepartment of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Aurelia Cristina NechiforAnalytical Chemistry and Environmental Engineering Department, Polytechnic University of Bucharest, 011061 Bucharest, Romania.
Tapan BehlDepartment of Pharmacology, Chitkara College of Pharmacy, Chitkara University, Punjab 140401, India.
Chenmala KarthikaDepartment of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty 643001, India.
Manuela StoicescuDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Mihai Alexandru MunteanuDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.ORCID 0000-0002-4538-7574
Cristiana BusteaDepartment of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Simona BungauDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania.ORCID 0000-0003-3236-1292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extensive experimental, clinical, and epidemiological evidence has explained and proven that products of natural origin are significantly important in preventing and/or ameliorating various disorders, including different types of cancer that researchers are extremely focused on. Among these studies on natural active substances, one can distinguish the emphasis on resveratrol and its properties, especially the potential anticancer role. Resveratrol is a natural product proven for its therapeutic activity, with remarkable anti-inflammatory properties. Various other benefits/actions have also been reported, such as cardioprotective, anti-ageing, antioxidant, etc. and its rapid digestion/absorption as well. This review aims to collect and present the latest published studies on resveratrol and its impact on cancer prevention, molecular signals (especially p53 protein participation), and its therapeutic prospects. The most recent information regarding the healing action of resveratrol is presented and concentrated to create an updated database focused on this topic presented above.

Indexed as

Antineoplastic Agents, PhytogenicHumansNeoplasmsResveratrolTumor Suppressor Protein p53Antineoplastic Agents, PhytogenicResveratrolTumor Suppressor Protein p53cancer preventioncardio protectionclinical trialsmolecular signalsnatural compoundp53polyphenolred wineresveratrol

Identifiers

PMID34500758
PMCPMC8433711

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.