Evidence map›Paper›PMID 34500750›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis, Crystal Structure and Bioactivity of Phenazine-1-carboxylic Acylhydrazone Derivatives.

Shouting Wu, Xi Liang, Fang Luo, Hua Liu, Lingyi Shen, Xianjiong Yang, Yali Huang, Hong Xu, Ning Wu, Qilong Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Shouting WuResearch Center for Molecular Medical Engineering, Department of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Xi LiangResearch Center for Molecular Medical Engineering, Department of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Fang LuoDepartment of Biology & Engineering, Guizhou Medical University, Guiyang 550004, China.
Hua LiuDepartment of Biology & Engineering, Guizhou Medical University, Guiyang 550004, China.
Lingyi ShenResearch Center for Molecular Medical Engineering, Department of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Xianjiong YangResearch Center for Molecular Medical Engineering, Department of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Yali HuangResearch Center for Molecular Medical Engineering, Department of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Hong XuResearch Center for Molecular Medical Engineering, Department of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Ning WuResearch Center for Molecular Medical Engineering, Department of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Qilong ZhangResearch Center for Molecular Medical Engineering, Department of Basic Medical Sciences, Guizhou Medical University, Guiyang 550004, China.
Carl RedshawDepartment of Chemistry, University of Hull, Cottingham Road, Hull HU6 7RX, UK.ORCID 0000-0002-2090-1688
Guiyang Medical University · CNUniversity of Hull · GB

Funding

Guizhou Provincial Natural Science Foundation [2019] 2792 19NSP042National Natural Science Foundation of China 22065009, 22066007
6 · The paper itself

Abstract

A phenazine-1-carboxylic acid intermediate was synthesized from the reaction of aniline and 2-bromo-3-nitro-benzoic acid. It was then esterified and reacted with hydrazine hydrate to afford phenazine-1-carboxylic hydrazine. Finally, 10 new hydrazone compounds

Indexed as

A549 CellsAntineoplastic AgentsCell ProliferationCell SurvivalDose-Response Relationship, DrugDrug Screening Assays, AntitumorHeLa CellsHumansHydrazonesMolecular StructurePhenazinesStructure-Activity Relationship1-phenazinecarboxylic acidAntineoplastic AgentsHydrazonesPhenazinesacylhydrazone compoundsanticancer activitycrystal structurephenazine-1-carboxylic acid

Identifiers

PMID34500750
PMCPMC8434039
OpenAlexW3197122604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.