Evidence map›Paper›PMID 34500664›Full record

ArticleMolecules (Basel, Switzerland)2021

GC-MS, LC-MS/MS, Docking and Molecular Dynamics Approaches to Identify Potential SARS-CoV-2 3-Chymotrypsin-Like Protease Inhibitors from

Muhammad Sulaiman Zubair, Saipul Maulana, Agustinus Widodo, Ramadanil Pitopang, Muhammad Arba, Maywan Hariono

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Anti-Melanogenic Activity of Ethanolic Extract fromAntioxidants (Basel, Switzerland) · 2024
    Article
  6. Review
  7. Article
  8. Journal of public health in Africa · 2023
    Article
  9. Small molecules in the treatment of COVID-19.Signal transduction and targeted therapy · 2022
    Review
  10. Article
  11. Inhibition of the main protease of SARS-CoV-2 (MComputational and structural biotechnology journal · 2022
    Review
  12. Article
  13. Review
  14. Article
  15. The Future ofMolecules (Basel, Switzerland) · 2021
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Muhammad Sulaiman ZubairDepartment of Pharmacy, Faculty of Science, Tadulako University, Palu 94118, Indonesia.ORCID 0000-0002-3065-0480
Saipul MaulanaDepartment of Pharmacy, Faculty of Science, Tadulako University, Palu 94118, Indonesia.
Agustinus WidodoDepartment of Pharmacy, Faculty of Science, Tadulako University, Palu 94118, Indonesia.
Ramadanil PitopangDepartment of Biology, Faculty of Science, Tadulako University, Palu 94118, Indonesia.
Muhammad ArbaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Halu Oleo University, Kendari 93231, Indonesia.
Maywan HarionoDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Sanata Darma University, Yogyakarta 55282, Indonesia.ORCID 0000-0001-6757-2116

Funding

The Directorate General of Higher Education, The Ministry of Education. Culture, Research and Technology, Republic of Indonesia 919a/UN28.2/PL/2021
6 · The paper itself

Abstract

This study aims to identify and isolate the secondary metabolites of

Indexed as

COVID-19 Drug TreatmentCoronavirus 3C ProteasesCoronavirus Protease InhibitorsCrystallography, X-RayEnzyme AssaysGas Chromatography-Mass SpectrometryHumansLactamsLeucineMagnetic Resonance SpectroscopyMolecular Docking SimulationMolecular Dynamics SimulationPlant ExtractsPyrrolidinesSARS-CoV-2Structure-Activity Relationship3C-like proteinase, SARS-CoV-2Coronavirus 3C ProteasesCoronavirus Protease InhibitorsGC376LactamsLeucinePlant ExtractsPyrrolidinesSulfonic Acids24-Methylcholesta-7-en-3β-on3CL ProteaseLC-MS/MSSARS-CoV-2SteroidsZingiber officinale

Identifiers

PMID34500664
PMCPMC8434146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.