ArticleMolecules (Basel, Switzerland)2021
Diversity of the Chemical Profile and Biological Activity of
Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Food Crops (Poaceae, Solanaceae, and Fabaceae) with Anti-Cancer Nutraceutical Prospects: A Review of Plant Extracts.Molecules (Basel, Switzerland) · 2026Review
- Eco-friendly solutions for Dactylopius opuntiae (Cockerell) (Hemiptera : Dactylopiidae) control using plant extracts and entomopathogenic fungi.Scientific reports · 2026Article
- Metabolomic profiling of pepper germplasm resources and its correlation with color, shape, and pungency traits.Food chemistry: X · 2025Article
- Combined effects of entomopathogenic fungi, plant extracts, and biorational insecticides on Morocain endemic bush cricketFrontiers in microbiology · 2025Article
- Phytochemical Profile, Antioxidant and Cytotoxic Potential ofPharmaceutics · 2024Article
- Phenolic Compounds in Fractionated Blackcurrant Leaf Extracts in Relation to the Biological Activity of the Extracts.Molecules (Basel, Switzerland) · 2023Article
- Special Issue "Natural Plant Substances-Structural and Application Aspects: A Theme Issue in Honor of Professor Wieslaw Oleszek".Molecules (Basel, Switzerland) · 2022Article
- Dietary Polyphenols: Extraction, Identification, Bioavailability, and Role for Prevention and Treatment of Colorectal and Prostate Cancers.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ethanol extracts of two types of pepper (sweet and hot) were separated into fractions with increasing lipophilicity. After drying the extracts and fractions, their chemical composition, anti-radical activity in the DPPH radical system, and cytotoxic activity against PC-3 and HTC-116 cells were determined. A detailed qualitative analysis of the fractions was performed with the LC-QTOF-MS method. It was found that the chemical composition of pepper fractions did not always reflect their biological activity. The highest antiradical activity was detected in the fraction eluted with 40% methanol from sweet pepper. The highest total content of phenolic compounds was found in an analogous fraction from hot pepper, and this fraction showed the strongest cytotoxic effect on the PC-3 tumour line. The LC-MS analysis identified 53 compounds, six of which were present only in sweet pepper and four only in hot pepper. The unique chemical composition of the extracts was found to modulate their biological activity, which can only be verified experimentally.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.