When UDG and hAPE1 Meet Cyclopurines. How (5'

Michał Szewczuk, Karolina Boguszewska, Julia Kaźmierczak-Barańska, Bolesław T Karwowski

Open access · goldAbstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 47% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Regulation of base excision repair during adipogenesis and osteogenesis of bone marrow-derived mesenchymal stem cells.Scientific reports · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michał SzewczukDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Poland.ORCID 0000-0002-5680-6594

Karolina BoguszewskaDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Poland.ORCID 0000-0003-3772-8540

Julia Kaźmierczak-BarańskaDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Poland.ORCID 0000-0001-8560-5727

Bolesław T KarwowskiDNA Damage Laboratory of Food Science Department, Faculty of Pharmacy, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Poland.ORCID 0000-0001-6922-7834

Medical University of Lodz · PL

Funding

Narodowym Centrum Nauki 2016/23/B/NZ7/03367

6 · The paper itself

Abstract

Ionizing radiation is a factor that seriously damages cellular mechanisms/macromolecules, e.g., by inducing damage in the human genome, such as 5',8-cyclo-2'-deoxypurines (cdPus). CdPus may become a component of clustered DNA lesions (CDL), which are notably unfavorable for the base excision repair system (BER). In this study, the influence of 5'

Indexed as

DeoxyadenosinesDeoxyguanosineDNADNA-(Apurinic or Apyrimidinic Site) LyaseDNA DamageDNA RepairHumansOligonucleotidesUracil-DNA Glycosidase8,5'-cyclo-2'-deoxyadenosineAPEX1 protein, humanDeoxyadenosinesDeoxyguanosineDNADNA-(Apurinic or Apyrimidinic Site) LyaseOligonucleotidesUracil-DNA Glycosidase5′,8-cyclo-2′-deoxyadenosine (cdA)5′,8-cyclo-2′-deoxyguanosine (cdG)base excision repairhuman AP site endonuclease 1tandem lesionsuracil-DNA glycosylase

Identifiers

PMID34500606

DOI10.3390/molecules26175177

PMCPMC8434022

OpenAlexW3195053478

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.