Evidence map›Paper›PMID 34500572›Full record

ReviewMolecules (Basel, Switzerland)2021

Phages and Enzybiotics in Food Biopreservation.

José Ramos-Vivas, María Elexpuru-Zabaleta, María Luisa Samano, Alina Pascual Barrera, Tamara Y Forbes-Hernández, Francesca Giampieri, Maurizio Battino

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Efficacy ofMicrobiology spectrum · 2025
    Article
  6. Review
  7. Endolysins as Effective Agents for DecontaminatingInternational journal of molecular sciences · 2025
    Article
  8. Review
  9. Review
  10. Phage diversity in One Health.Essays in biochemistry · 2024
    Review
  11. Article
  12. Review
  13. Safety Properties ofFoods (Basel, Switzerland) · 2023
    Review
  14. Control ofAntibiotics (Basel, Switzerland) · 2023
    Article
  15. Review
  16. Potential Applications of Thermophilic Bacteriophages in One Health.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Article
  19. Broad-SpectrumViruses · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

José Ramos-VivasResearch Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.ORCID 0000-0001-8795-519X
María Elexpuru-ZabaletaResearch Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.
María Luisa SamanoResearch Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.ORCID 0000-0002-7097-9352
Alina Pascual BarreraDepartment of Project Management, Universidad Internacional Iberoamericana, Campeche 24560, Mexico.
Tamara Y Forbes-HernándezDepartment of Analytical and Food Chemistry, CITACA, CACTI, University of Vigo, 36310 Vigo, Spain.
Francesca GiampieriDepartment of Clinical Sciences, Polytechnic University of Marche, 60131 Ancona, Italy.ORCID 0000-0002-8151-9132
Maurizio BattinoDepartment of Clinical Sciences, Polytechnic University of Marche, 60131 Ancona, Italy.ORCID 0000-0002-7250-1782
Ibero American University · MXJiangsu University · CNMarche Polytechnic University · ITUniversidade de Vigo · ESUniversidad Europea del Atlántico · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presently, biopreservation through protective bacterial cultures and their antimicrobial products or using antibacterial compounds derived from plants are proposed as feasible strategies to maintain the long shelf-life of products. Another emerging category of food biopreservatives are bacteriophages or their antibacterial enzymes called "phage lysins" or "enzybiotics", which can be used directly as antibacterial agents due to their ability to act on the membranes of bacteria and destroy them. Bacteriophages are an alternative to antimicrobials in the fight against bacteria, mainly because they have a practically unique host range that gives them great specificity. In addition to their potential ability to specifically control strains of pathogenic bacteria, their use does not generate a negative environmental impact as in the case of antibiotics. Both phages and their enzymes can favor a reduction in antibiotic use, which is desirable given the alarming increase in resistance to antibiotics used not only in human medicine but also in veterinary medicine, agriculture, and in general all processes of manufacturing, preservation, and distribution of food. We present here an overview of the scientific background of phages and enzybiotics in the food industry, as well as food applications of these biopreservatives.

Indexed as

AnimalsAnti-Bacterial AgentsBacteriaBacteriophagesFoodFood IndustryFood PreservationHumansAnti-Bacterial Agentsbacteriophagebiopreservationendolysinenzybiotics

Identifiers

PMID34500572
PMCPMC8433972
OpenAlexW3195955340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.