Evidence map›Paper›PMID 34500482›Full record

ArticleAmerican journal of perinatology2023

Complicated Intubations are Associated with Bronchopulmonary Dysplasia in Very Low Birth Weight Infants.

Tara Glenn, Linnea Fischer, Ashley Markowski, Cara Beth Carr, Sindhoosha Malay, Anna Maria Hibbs

Open access · greenAbstract read
In one paragraph

Article in American journal of perinatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tara GlennDepartment of Pediatrics, Division of Neonatology, UH Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Linnea FischerDepartment of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Ashley MarkowskiDepartment of Pediatrics, Division of Neonatology, UH Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Cara Beth CarrDepartment of Pediatrics, Division of Neonatology, UH Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Sindhoosha MalayDepartment of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Anna Maria HibbsDepartment of Pediatrics, Division of Neonatology, UH Rainbow Babies and Children's Hospital, Cleveland, Ohio.
Case Western Reserve University · USRainbow Babies & Children's Hospital · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
Patient-Oriented Research and Mentoring Program in Prematurity-Associated Pulmonary MorbidityK24HL143291 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI HIBBS, ANNA MARIA · 2018 to 2022
$598k
NCATS NIH HHS UL1 TR002548NCATS NIH HHS UM1 TR004528NHLBI NIH HHS K24 HL143291
6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the association between desaturation <60% (severe desaturation) during intubation and a total number of intubation attempts in the first week of life in very low birth weight (VLBW) infants with adverse long-term outcomes including bronchopulmonary dysplasia (BPD) and severe periventricular/intraventricular hemorrhage grade 3 or 4 (PIVH). STUDY

designA retrospective chart review was performed on VLBW infants intubated in the neonatal intensive care unit during the first week of life between January 2017 and July 2020. Descriptive tables were generated for two outcomes including BPD and PIVH. Multivariable logistic regression was performed for each outcome including significant predictors that differed between groups with a

resultsA total of 146 patients were included. Patients with BPD or PIVH had a lower gestational age, and patients with BPD had a lower BW. Patients with BPD had a greater number of intubation attempts in the first week of life (4 vs. 3,

conclusionThe odds of developing BPD for VLBW infants were higher with increased intubation attempts and intubation encounters. In a post hoc analysis, the odds of developing BPD were also higher with desaturation during intubation. Further research is needed to determine mechanisms of the relationship between complicated intubations and the development of BPD. KEY POINTS: · Neonatal intubations often require multiple attempts.. · Neonates frequently desaturate during intubation.. · Intubation attempts are positively associated with BPD.. · Severe desaturation may be positively associated with BPD..

Indexed as

Bronchopulmonary DysplasiaBirth WeightGestational AgeHumansInfantInfant, NewbornInfant, Very Low Birth WeightIntubation, IntratrachealRetrospective Studies

Identifiers

PMID34500482
PMCPMC9239052
OpenAlexW3198785814

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.