Evidence map›Paper›PMID 34500362›Full record

ArticleEnvironment international2021

The effects of radiofrequency electromagnetic fields exposure on tinnitus, migraine and non-specific symptoms in the general and working population: A protocol for a systematic review on human observational studies.

Martin Röösli, Stefan Dongus, Hamed Jalilian, Maria Feychting, John Eyers, Ekpereonne Esu, Chioma Moses Oringanje, Martin Meremikwu, Xavier Bosch-Capblanch

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 6 countries.

Martin RöösliSwiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland; University of Basel, Petersplatz 1, CH-4003 Basel, Switzerland. Electronic address: martin.roosli@swisstph.ch.
Stefan DongusSwiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland; University of Basel, Petersplatz 1, CH-4003 Basel, Switzerland. Electronic address: stefan.dongus@swisstph.ch.
Hamed JalilianDepartment of Occupational Health Engineering, Research Center for Environmental Pollutants, Faculty of Health, Qom University of Medical Sciences, Qom, Iran. Electronic address: jalilianh@hotmail.com.
Maria FeychtingUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: maria.feychting@ki.se.
John EyersInternational Initiative for Impact Evaluation, 3ie, c/o LIDC, 20 Bloomsbury Square, London WC1A 2NS, United Kingdom. Electronic address: johneyers@hotmail.com.
Ekpereonne EsuDepartment of Public Health, College of Medical Sciences, University of Calabar, Calabar, Nigeria. Electronic address: ekpereonneesu@gmail.com.
Chioma Moses OringanjeDepartment of Biology, College of Art & Sciences, Xavier University, Cincinnati, OH, USA. Electronic address: chyoma12@yahoo.com.
Martin MeremikwuFaculty of Medicine, College of Medical Sciences, University of Calabar, Calabar, Nigeria. Electronic address: mmeremiku@yahoo.co.uk.
Xavier Bosch-CapblanchSwiss Tropical and Public Health Institute, Socinstrasse 57, CH-4051 Basel, Switzerland; University of Basel, Petersplatz 1, CH-4003 Basel, Switzerland. Electronic address: x.bosch@swisstph.ch.
Swiss Tropical and Public Health Institute · CHUniversity of Calabar · NGKarolinska Institutet · SELondon International Development Centre · GBQom University of Medical Science and Health Services · IRUniversity of Basel · CHXavier University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundApplications emitting radiofrequency electromagnetic fields (RF-EMF; 100 kHz to 300 GHz) are widely used for communication (e.g. mobile phones), in medicine (diathermy) and in industry (RF heaters). Concern has been raised that RF-EMF exposure affects health related quality of life, because a part of the population reports to experience a variety of symptoms related to low exposure levels below regulatory limits.

objectivesTo systematically review the effects of longer-term or repeated local and whole human body RF-EMF exposure on the occurrence of symptoms evaluating migraine, tinnitus, headaches, sleep disturbances and composite symptom scores as primary outcomes.

methodsWe will follow the WHO handbook for guideline development. For the development of the systematic review protocol we considered handbook for conducting systematic reviews for health effects evaluations from the National Toxicology Program-Office of Health Assessment and Translation (NTP-OHAT) and COSTER (Recommendations for the conduct of systematic reviews in toxicology and environmental health research). ELIGIBILITY CRITERIA: Peer-reviewed epidemiological studies in the general population or workers aiming to investigate the association between local or whole-body RF-EMF exposure for at least one week and symptoms are eligible for inclusion. Only cohort, case-control and panel studies will be included. INFORMATION SOURCES: We will search the scientific literature databases Medline, Web of Science, PsycInfo, Cochrane Library, Epistemonikos and Embase, using a predefined search strategy. This search will be supplemented by a search in the EMF-Portal and checks of reference lists of relevant papers and reviews. STUDY APPRAISAL AND SYNTHESIS

methodData from included papers will be extracted according to predefined forms. Findings will be summarized in tables, graphical displays and in a narrative synthesis of the available evidence, complemented with meta-analyses. We will separately review effects of local, far field and occupational exposure. RISK OF BIAS: The internal validity of included studies will be assessed using the NTP-OHAT Risk of Bias Rating Tool for Human and Animal Studies, elaborated to observational RF-EMF studies. EVIDENCE APPRAISAL: To rate certainty of the evidence, we will use the OHAT GRADE-based approach for epidemiological studies. FRAMEWORK AND

fundingThis protocol concerns one of the ten different systematic reviews considered in a larger systematic review of the World Health Organization to assess potential health effects of exposure to RF-EMF in the general and working population. REGISTRATION: PROSPERO CRD42021239432.

Indexed as

Migraine DisordersTinnitusAnimalsElectromagnetic FieldsHumansObservational Studies as TopicQuality of LifeSystematic Reviews as TopicHeadacheMicrowaveMigraineNon-specific symptomsSleepTinnitus

Identifiers

PMID34500362
PMCPMC8484767
OpenAlexW3198712594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.