Evidence map›Paper›PMID 34499804›Full record

ArticleImmunity, inflammation and disease2021

Long-term effects of obesity on COVID-19 patients discharged from hospital.

Luorui Shang, Li Wang, Fangyuan Zhou, Jinxiao Li, Yuhan Liu, Shenglan Yang

Abstract read
In one paragraph

Article in Immunity, inflammation and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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  7. Article
  8. Insulin Resistance in Long COVID-19 Syndrome.Journal of personalized medicine · 2024
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  10. Article
  11. Review
  12. Review
  13. The Dual Pandemics of COVID-19 and Obesity: Bidirectional Impact.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2022
    Review
  14. Review
  15. Obesity and Coronavirus Disease 2019.Journal of translational internal medicine · 2022
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luorui ShangDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0003-3562-8108
Li WangDepartment of Emergency Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Fangyuan ZhouDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jinxiao LiDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yuhan LiuDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shenglan YangDepartment of Integrated Traditional Chinese and Western Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

National Natural Science Foundation of China 81673760National Natural Science Foundation of China 81874397
6 · The paper itself

Abstract

introductionObesity has been reported as a risk factor for COVID-19 prognosis. However, the long-term effects of obesity on patients discharged from the hospital are unclear, and the present study aims to address this issue.

methodsA cohort study was conducted using data from patients diagnosed with COVID-19 who were discharged from Wuhan Union Hospital between February 20, 2020, and March 20, 2020. The 118 patients with COVID-19 were divided into the non-obesity group and the obesity group according to their body mass index (BMI). All the patients were invited to fill out a series of scales to assess cardiopulmonary function. Data on population baseline characteristics, clinical manifestations, laboratory examinations, chest computed tomography (CT), and lung function were collected and analyzed.

resultsThe clinical manifestations and pathological changes on CT images of obese patients were more serious after discharge than those of non-obese patients. In addition, we found significant abnormalities in metabolic indicators such as blood lipids, uric acid, and liver function in obese patients. Most importantly, the antibody titer of COVID-19 obese patients was inversely correlated with BMI.

conclusionIn the long term, obesity affects clinical manifestations, immune function and endocrine metabolism in patients discharged after recovering from COVID-19.

Indexed as

COVID-19Patient DischargeCohort StudiesHospitalsHumansObesitySARS-CoV-2antibody titerblood lipidbody mass indexCOVID-19obesitySARS-CoV-2

Identifiers

PMID34499804
PMCPMC8589408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.