ArticlePsycho-oncology2021
Mortality from cancer in people with severe mental disorders in Emilia Romagna Region, Italy.
Article in Psycho-oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Colorectal cancer mortality in persons with severe mental illness: a scoping review with meta-analyses of observational studies.Acta oncologica (Stockholm, Sweden) · 2025Pooled it
- All-cause and cause-specific mortality among people with bipolar disorder: a large-scale systematic review and meta-analysis.Molecular psychiatry · 2023Pooled it
- Health behaviours and telomere biology in severe mental disorders.Translational psychiatry · 2026Article
- Bipolar disorder in oncology: Considerations for the psychiatrist.Journal of mood and anxiety disorders · 2026Review
- Outcomes after pulmonary resection for malignancy in patients with severe and persistent mental illness.Journal of cardiothoracic surgery · 2026Article
- A Descriptive Thematic Review of Barriers, Facilitators, and Recommendations for Cancer Screening Uptake Among Community Dwelling Adults with Mental Ill-Health.International journal of environmental research and public health · 2026Review
- Psychosomatics at the threshold: cancer, mood disorders, and the mental pain of death - where precision medicine meets spirituality.Frontiers in psychiatry · 2026Article
- Inequalities in cancer mortality between people with and without disability: A nationwide data linkage study of 10 million adults in Australia.PLoS medicine · 2026Article
- The Challenging Problems of Cancer and Serious Mental Illness.Current psychiatry reports · 2025Review
- The double burden of severe mental illness and cancer: a population-based study on colorectal cancer care pathways from screening to end-of-life care.Epidemiology and psychiatric sciences · 2024Article
- Palliative Care Psychiatry: Building Synergy Across the Spectrum.Current psychiatry reports · 2024Review
- Association between cumulative exposure periods of flupentixol or any antipsychotics and risk of lung cancer.Communications medicine · 2023Article
- Establishment of a Public Mental Health Database for Research Purposes in the Ferrara Province: Development and Preliminary Evaluation Study.JMIR medical informatics · 2023Article
- Cancer mortality in Common Mental Disorders: A 10-year retrospective cohort study.Social psychiatry and psychiatric epidemiology · 2023Article
- Breast Cancer Care Pathways for Women with Preexisting Severe Mental Disorders: Evidence of Disparities in France?Journal of clinical medicine · 2023Article
- Mortality from cancer in people with severe mental disorders in Emilia Romagna Region, Italy.Psycho-oncology · 2021Article
Corrections and comments
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine cancer-related mortality in patients with severe mental disorders (SMI) in the Emilia Romagna (ER) Region, Northern Italy, during the period 2008-2017 and compare it with the regional population.
methodsWe used the ER Regional Mental Health Registry identifying all patients aged ≥18 years who had received an ICD-9CM system diagnosis of SMI (i.e., schizophrenia or other functional psychosis, mania, or bipolar affective disorders) during a 10-year period (2008-2017). Information on deaths (date and causes of death) were retrieved through the Regional Cause of Death Registry. Comparisons were made with the deaths and cause of deaths of the regional population over the same period.
resultsAmongst 12,385 patients suffering from SMI (64.1% schizophrenia spectrum and 36.9% bipolar spectrum disorders), 24% (range 21%-29%) died of cancer. In comparison with the general regional population, the mortality for cancer was about 50% higher among patients with SMI, irrespective if affected by schizophrenia or bipolar disorders. As for the site-specific cancers, significant excesses were reported for stomach, central nervous system, respiratory, and pancreas cancer with a variability according to psychiatric diagnosis and gender.
conclusionsPatients suffering from SMI had higher mortality risk than the regional population with some differences according to cancer type, gender, and psychiatric diagnosis. Proper cancer preventive and treatment interventions, including more effective risk modification strategies (e.g., smoking cessation, dietary habits) and screening for cancer, should be part of the agenda of all mental health departments in conjunction with other health care organizations, including psycho-oncology.
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