SynthesisPLoS neglected tropical diseases2021
The impact of access to water supply and sanitation on the prevalence of active trachoma in Ethiopia: A systematic review and meta-analysis.
Synthesis in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 6 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 6 syntheses or guidelines pooled it, 12 citations in OpenAlex.
- Predictors of trachoma among children aged 1-9 years in Ethiopia: a comprehensive systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Pooled it
- Pooled it
- Active trachoma among children aged 1-9 years in Ethiopia: A meta-analysis from 2019 to 2024.PloS one · 2025Pooled it
- Prevalence of active trachoma among 1-9 years of age children in Ethiopia: a systematic review and meta-analysis.BMJ open · 2024Pooled it
- TFOS lifestyle: Impact of societal challenges on the ocular surface.The ocular surface · 2023Pooled it
- Dynamics of trachoma infection in West Africa revealed by a hidden state model.PLoS computational biology · 2026Article
- Trachoma Prevalence and Associated WASH and Behavioral Risk Among Rural Communities of North Gondar Zone, Ethiopia: A Community-Based Cross-Sectional Study.Journal of tropical medicine · 2026Article
- Analysis and forecast of the disease burden of trachoma in China and the Global Population over 15 years of age, 1990-2021.PLoS neglected tropical diseases · 2025Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrachoma is a worldwide infectious disease causing blindness. Trachoma continued as a public health problem in Ethiopia due to a lack of sanitation and inadequate prevention strategies. This study aimed to identify the impact of water supply and sanitation intervention on preventing active trachoma among children.
methodsSystematic literature searches were performed from 4 international databases. The search involved articles published from January 1995 up to March 2019. The Cochran Q and I2 statistical tests were used to check heterogeneity among the studies. A random-effect meta-analysis was employed to determine the pooled estimates with a 95% confidence interval (CI). Data analysis was performed using the CMA V.3 and RevMan 5 software program, and the result of the systematic review was reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
findingsOut of 211 studies screened for the analysis, only 29 studies were finally included in this systematic review and meta-analysis. The result revealed factors that are significantly associated with increased odds of active trachoma. Accordingly, households with no access to toilet facilities (odds ratio [OR]: 2.04, 95% CI: 1.75-2.38), no access to improved water (OR: 1.58, 95% CI: 1.27-1.96), and do not practice regular face washing for children (OR: 4.19, 95% CI: 3.02-5.81) have shown increased odds of active trachoma. Besides, the results show a higher prevalence of active trachoma among children who did not wash their faces with soap and frequently.
conclusionsThe study found strong evidence that lack of access to water, sanitation, and hygiene (WASH) was associated with increased prevalence of active trachoma among children. Therefore, a comprehensive and partnership-oriented program is needed to tackle the problem, but further study will be required to strengthen its implementation.
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