Evidence map›Paper›PMID 34499337›Full record

SynthesisSports medicine (Auckland, N.Z.)2022

The Acute Effects of Exercising in Air Pollution: A Systematic Review of Randomized Controlled Trials.

Andy Hung, Hannah Nelson, Michael S Koehle

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Effects of the inhaled dose of air pollution on health: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Review
  10. Effects of Air Pollution on the Health of Older Adults during Physical Activities: Mapping Review.International journal of environmental research and public health · 2023
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andy HungSchool of Kinesiology, The University of British Columbia, Vancouver, BC, Canada.ORCID http://orcid.org/0000-0002-6905-6323
Hannah NelsonSchool of Kinesiology, The University of British Columbia, Vancouver, BC, Canada.
Michael S KoehleSchool of Kinesiology, The University of British Columbia, Vancouver, BC, Canada. michael.koehle@ubc.ca.ORCID http://orcid.org/0000-0001-7026-8422
University of British Columbia · CA

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-2017-04519
6 · The paper itself

Abstract

backgroundThe acute effects of air pollution (AP) exposure during physical activity have been studied. However, comprehensive systematic reviews are lacking, particularly regarding moderate-to-vigorous physical activity (MVPA).

objectiveOur objective was to determine the acute health- and exercise-related effects of AP exposure during a bout of MVPA in healthy individuals.

methodsWe searched for randomized controlled trials in MEDLINE, Embase, Cochrane CENTRAL, SPORTDiscus, Agricultural and Environmental Science Database, ClinicalTrials.gov, International Standard Randomised Controlled Trial Number Registry, and the World Health Organization (WHO) International Clinical Trials Registry Platform up to July 2020 without language or date restrictions. Studies including healthy subjects engaging in a bout of MVPA while exposed to one or more of the following air pollutants were eligible: particulate matter, black carbon, carbon monoxide, nitrogen dioxide, ozone, diesel exhaust, and traffic-related air pollution (TRAP). Main outcome measures were markers of pulmonary function, symptoms, cardiovascular function, cognitive function, systemic inflammation, and exercise response. The evidence was synthesized by vote counting based on direction of effect.

resultsIn total, 53 studies were included in the systematic review. Studies employed a heterogeneous mix of exercise protocols, AP interventions, and measured outcomes. Pooled results suggest ozone exposure during MVPA has an adverse effect on pulmonary function (100% [95% confidence interval (CI) 88-100], p < 0.001; high-certainty evidence) and reported symptoms (88% [95% CI 69-96], p < 0.001; low-certainty evidence). The effect of exposure to carbon monoxide, nitrogen dioxide, small engine exhaust, or diesel exhaust during MVPA on health- and exercise-related outcomes is uncertain because of insufficient evidence and the low to very low certainty of available evidence. DISCUSSION: The evidence is strongest for ozone, exposure to which generally induced a reduction in pulmonary function and increased symptoms during MVPA. The research related to other outcome domains remains inconclusive. Although long-term exposure to AP is proven to be hazardous, the evidence for healthy individuals to forgo MVPA during periods of high (non-ozone) pollution remains weak.

trial registrationRetrospectively registered in PROSPERO (CRD42020188280) on 10 July 2020.

Indexed as

Air PollutionExerciseHealth StatusHumansRandomized Controlled Trials as Topic

Identifiers

PMID34499337
OpenAlexW3197420134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.