ReviewInsights into imaging2021
Quantitative ultrasound imaging of soft biological tissues: a primer for radiologists and medical physicists.
Review in Insights into imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04396288 (Characterization of Intra-osseous Vascular Response With Ultrasound Imaging on Healthy Volunteers), which is not on this map. Cited by 50 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Characterization of Intra-osseous Vascular Response With Ultrasound Imaging on Healthy Volunteers
Who cites it
50 citing papers in PubMed.
- Quantitative ultrasound evaluation of the thoracolumbar fascia after manual and acupuncture therapies: an exploratory mechanistic randomized controlled trial with a sequential within-subject phase.European radiology experimental · 2026Trial
- Impact of acquisition geometry on ultrasound-derived fat fraction measurements: implications for standardized acquisition and measurement interchangeability.Quantitative imaging in medicine and surgery · 2026Article
- Thoracolumbar fascia ultrasound and elastography biomarkers in low back pain: a systematic review of associations and responsiveness to intervention.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Research Progress and Translational Perspectives of Piezoelectric Materials in Dental Implant Surface Engineering.Journal of functional biomaterials · 2026Review
- Ultrasound Radiomics in Pediatric Imaging: Current Applications, Challenges, and Future Directions Toward Clinical Implementation.Diagnostics (Basel, Switzerland) · 2026Review
- Musculoskeletal Ultrasound and Protein-Based Hydrogels: Novel Approaches for the Diagnosis and Treatment of Sports Injuries.Polymers · 2026Review
- Machine learning for the prediction of three-year survival in locally advanced breast cancer patients receiving neoadjuvant chemotherapy using quantitative ultrasound imaging.Scientific reports · 2026Article
- Characterizing tendon microstructure using metrics associated with the angular dependence of ultrasound backscatter.The Journal of the Acoustical Society of America · 2026Article
- Ultrasound Attenuation Coefficient as a Biomarker of Hepatic Steatosis: State of the Art and Software Evaluation.Journal of clinical medicine · 2026Review
- Early Detection of Liver Fibrosis Using Scatteromics Based on Multimodal QUS Envelope Statistics Imaging.Diagnostics (Basel, Switzerland) · 2026Article
- Improved imaging interfaces on a co-registered ultrasound and optical microscopy multiscale system.Journal of biomedical optics · 2026Article
- Ultrasound-guided structural fusion enhances the interpretability of electrical impedance tomography for layered tissue imaging.Journal of electrical bioimpedance · 2026Article
- Diagnostic Imaging of the Skeletal System: Overview of Applications in Human and Veterinary Medicine.Bioengineering (Basel, Switzerland) · 2025Review
- Synergistic Effects of Non-Ionizing Radiation in the Targeted Modification of Living Tissues.International journal of molecular sciences · 2025Review
- Structural Optimization and Simulation of Dual-Frequency Piezoelectric Micromachined Ultrasonic Transducers.Micromachines · 2025Article
- The Role of Quantitative Ultrasound in Monitoring Neoadjuvant Chemotherapy in Breast Cancer: A Narrative Review.Cancers · 2025Review
- Brain ultrasound radiomics identify textural differences in basal ganglia and white matter between full term newborns HIV-exposed uninfected and HIV-unexposed in Botswana.Early human development · 2025Observational
- Quantitative evaluation of muscle quality and quantity using an ultrasound radio frequency signal.Journal of orthopaedic surgery and research · 2025Article
- Impact of sample handling protocols on soft tissue attenuation coefficient and morphology.Journal of biomedical optics · 2025Article
- Quantitative ultrasound moment-based double Nakagami distribution method.Medical physics · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Quantitative ultrasound (QUS) aims at quantifying interactions between ultrasound and biological tissues. QUS techniques extract fundamental physical properties of tissues based on interactions between ultrasound waves and tissue microstructure. These techniques provide quantitative information on sub-resolution properties that are not visible on grayscale (B-mode) imaging. Quantitative data may be represented either as a global measurement or as parametric maps overlaid on B-mode images. Recently, major ultrasound manufacturers have released speed of sound, attenuation, and backscatter packages for tissue characterization and imaging. Established and emerging clinical applications are currently limited and include liver fibrosis staging, liver steatosis grading, and breast cancer characterization. On the other hand, most biological tissues have been studied using experimental QUS methods, and quantitative datasets are available in the literature. This educational review addresses the general topic of biological soft tissue characterization using QUS, with a focus on disseminating technical concepts for clinicians and specialized QUS materials for medical physicists. Advanced but simplified technical descriptions are also provided in separate subsections identified as such. To understand QUS methods, this article reviews types of ultrasound waves, basic concepts of ultrasound wave propagation, ultrasound image formation, point spread function, constructive and destructive wave interferences, radiofrequency data processing, and a summary of different imaging modes. For each major QUS technique, topics include: concept, illustrations, clinical examples, pitfalls, and future directions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.