Evidence map›Paper›PMID 34499215›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

Caregiver bereavement outcomes in advanced cancer: associations with quality of death and patient age.

Kenneth Mah, Nadia Swami, Ashley Pope, Craig C Earle, Monika K Krzyzanowska, Rinat Nissim, Sarah Hales, Gary Rodin, Breffni Hannon, Camilla Zimmermann

Open access · bronzeAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Neurobiology of Pet Loss Grief: A Review from a One Health Perspective.Animals : an open access journal from MDPI · 2026
    Review
  2. Article
  3. Factors associated with end-of-life quality in terminally ill cancer patients' last six months of life: a longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Associations between palliative-care consultations and end-of-life quality in cancer patients' last 6 months.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  9. Article
  10. Article
  11. Caregiver bereavement outcomes in advanced cancer: associations with quality of death and patient age.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  12. Reply to K. Kajiwara et al. concerning "Caregiver bereavement outcomes in advanced cancer: associations with quality of death and patient age".Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Kenneth MahDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Nadia SwamiDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Ashley PopeDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Craig C EarleOdette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Monika K KrzyzanowskaDivision of Medical Oncology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Rinat NissimDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Sarah HalesDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Gary RodinDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Breffni HannonDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Camilla ZimmermannDepartment of Supportive Care, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. camilla.zimmermann@uhn.ca.ORCID http://orcid.org/0000-0003-4889-0244
University Health Network · CASunnybrook Health Science Centre · CA

Funding

Canadian Cancer Society #017257, #020509, #700862CIHR #152996
6 · The paper itself

Abstract

purposeWe investigated relationships between domains of quality of dying and death in patients with advanced cancer and their caregivers' bereavement outcomes and the moderating effect of patient age at death.

methodsBereaved caregivers of deceased patients with advanced cancer who had participated in an early palliative care trial completed measures of grief (Texas Revised Inventory of Grief [TRIG]), complicated grief (Prolonged Grief Inventory [PG-13]), and depression (Center for Epidemiologic Studies-Depression [CESD-10]). They also completed the Quality of Dying and Death measure (QODD), which assesses patients' symptom control, preparation for death, connectedness with loved ones, and sense of peace with death.

resultsA total of 157 bereaved caregivers completed the study. When patient age × QODD subscale interactions were included, greater death preparation was related to less grief at patient death (past TRIG: β =  - .25, p = .04), less current grief (present TRIG: β =  - .26, p = .03), less complicated grief (PG-13: β =  - .37, p = .001), and less depression (CESD-10: β =  - .35, p = .005). Greater symptom control was related to less current grief (present TRIG: β =  - .27, p = .02), less complicated grief (PG-13: β =  - .24, p = .03), and less depression (CESD-10: β =  - .29, p = .01). Significant patient age × connectedness interaction effects for current grief (present TRIG: β = .30, p = .02) and complicated grief (PG-13: β = .29, p = .007) indicated that, with less connectedness, younger patient age at death was associated with greater caregiver grief.

conclusionBetter end-of-life death preparation and symptom control for patients with cancer may attenuate later caregiver grief and depression. Less connectedness between younger patients and their families may adversely affect caregiver grief.

Indexed as

BereavementNeoplasmsCaregiversGriefHumansPalliative CareAge factorsBereavementCancerCaregiversEnd-of-life careQuality of dying and death

Identifiers

PMID34499215
PMCPMC8426162
OpenAlexW3197937036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.