Evidence map›Paper›PMID 34498783›Full record

ArticleChembiochem : a European journal of chemical biology2021

TET-Like Oxidation in 5-Methylcytosine and Derivatives: A Computational and Experimental Study.

Niko S W Jonasson, Rachel Janßen, Annika Menke, Fabian L Zott, Hendrik Zipse, Lena J Daumann

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. A bioinorganic view on the potential chemical space of hydroxyphenylpyruvate dioxygenase-like (HPDL) enzymes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Article
  2. Article
  3. Selective Functionalisation of 5-Methylcytosine by Organic Photoredox Catalysis.Angewandte Chemie (International ed. in English) · 2023
    Article
  4. Selective Functionalisation of 5-Methylcytosine by Organic Photoredox Catalysis.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  5. Spectroscopic and in vitro Investigations of FeChembiochem : a European journal of chemical biology · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Niko S W JonassonDepartment of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 5-13, 81377, München, Germany.
Rachel JanßenDepartment of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 5-13, 81377, München, Germany.
Annika MenkeDepartment of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 5-13, 81377, München, Germany.
Fabian L ZottDepartment of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 5-13, 81377, München, Germany.
Hendrik ZipseDepartment of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 5-13, 81377, München, Germany.
Lena J DaumannDepartment of Chemistry, Ludwig-Maximilians-University Munich, Butenandtstr. 5-13, 81377, München, Germany.ORCID 0000-0003-2197-136X
Ludwig-Maximilians-Universität München · DE

Funding

Deutsche Forschungsgemeinschaft SFB 1309-325871075Studienstiftung des Deutschen Volkes
6 · The paper itself

Abstract

The epigenetic marker 5-methylcytosine (5mC) is an important factor in DNA modification and epigenetics. It can be modified through a three-step oxidation performed by ten-eleven-translocation (TET) enzymes and we have previously reported that the iron(IV)-oxo complex [Fe(O)(Py

Indexed as

5-MethylcytosineDNAHumansIron CompoundsKineticsModels, MolecularMolecular StructureOxidation-ReductionThermodynamicsUracil5-MethylcytosineDNAIron CompoundsUracil5-methylcytosinecomputational chemistryDNA methylationepigeneticssynthetic biology

Identifiers

PMID34498783
PMCPMC9293240
OpenAlexW3196608528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.