Evidence map›Paper›PMID 34498587›Full record

ArticleeLife2021

Structural basis for diguanylate cyclase activation by its binding partner in

Gukui Chen, Jiashen Zhou, Yili Zuo, Weiping Huo, Juan Peng, Meng Li, Yani Zhang, Tietao Wang, Lin Zhang, Liang Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Visualization of c-di-GMP in multicellularFrontiers in cell and developmental biology · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Gukui Chen *Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, ShaanXi, China.
Jiashen Zhou *Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Yili ZuoKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, ShaanXi, China.
Weiping HuoKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, ShaanXi, China.
Juan PengKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, ShaanXi, China.
Meng LiKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, ShaanXi, China.
Yani ZhangKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, ShaanXi, China.
Tietao WangKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, ShaanXi, China.ORCID 0000-0001-8540-436X
Lin ZhangDepartment of Pharmacology and Chemical Biology, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Liang ZhangDepartment of Pharmacology and Chemical Biology, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.ORCID 0000-0002-7672-1168
Haihua LiangKey Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, ShaanXi, China.ORCID 0000-0001-9639-1867
Ministry of Education of the People's Republic of China · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic-di-guanosine monophosphate (c-di-GMP) is an important effector associated with acute-chronic infection transition in

Indexed as

Bacterial ProteinsBinding SitesBiofilmsCatalysisDinucleoside PhosphatesEnzyme ActivationEscherichia coli ProteinsPhosphorus-Oxygen LyasesProtein BindingProtein ConformationPseudomonas aeruginosaSignal TransductionStructure-Activity RelationshipBacterial Proteinscyclic diadenosine phosphatediguanylate cyclaseDinucleoside PhosphatesEscherichia coli ProteinsPhosphorus-Oxygen Lyasescrystal structureinfectious diseasemicrobiologymolecular biophysicsPseudomonas aeruginosaSiaCSiaDstructural biology

Identifiers

PMID34498587
PMCPMC8457831
OpenAlexW3198750087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.