Evidence map›Paper›PMID 34498495›Full record

ReviewRegenerative medicine2021

Understanding neural stem cell regulation

Nafiisha Genet, Karen K Hirschi

Abstract readReview
In one paragraph

Review in Regenerative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nafiisha GenetDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.ORCID 0000-0002-2734-2882
Karen K HirschiDepartment of Cell Biology, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.ORCID 0000-0001-7116-0130

Funding

Neurovascular RegenerationR01EB016629 · NIBIB · YALE UNIVERSITY · PI HIRSCHI, KAREN KEMPER · 2014 to 2018
$4.8M
Endothelial Cell Cycle State and Cell FateR01HL146056 · NHLBI · UNIVERSITY OF VIRGINIA · PI HIRSCHI, KAREN KEMPER · 2019 to 2022
$2.1M
Integrated heart-liver-vascular systems for drug testing in human health and diseUH2EB017103 · NIBIB · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI VUNJAK-NOVAKOVIC, GORDANA · 2012 to 2013
$1.7M
NHLBI NIH HHS R01 HL146056NIBIB NIH HHS R01 EB016629NIBIB NIH HHS UH2 EB017103
6 · The paper itself

Abstract

The use of neural stem cell (NSC) therapy for the treatment of stroke patients is successfully paving its way into advanced phases of large-scale clinical trials. To understand how to optimize NSC therapeutic approaches, it is fundamental to decipher the crosstalk between NSC and other cells that comprise the NSC microenvironment (niche) and regulate their function,

Indexed as

Neural Stem CellsStrokeEndothelial CellsHumansNeurogenesisStem Cell NicheStem Cell Transplantationangiogenesisneural stem cellsneurogenesisstrokesubventricular zonevascular endothelial cells

Identifiers

PMID34498495
PMCPMC8656322

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.