Evidence map›Paper›PMID 34498465›Full record

ArticleJournal of the American Chemical Society2021

Coordination of the Copper Centers in Particulate Methane Monooxygenase: Comparison between Methanotrophs and Characterization of the Cu

Richard J Jodts, Matthew O Ross, Christopher W Koo, Peter E Doan, Amy C Rosenzweig, Brian M Hoffman

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. HChemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Histidine-Copper Site Variability in UiO-66: Monitoring Synthetic Intricacy with EPR Spectroscopy.Chemistry of materials : a publication of the American Chemical Society · 2025
    Article
  7. Structures of methane and ammonia monooxygenases in native membranes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Microbial oxidation of atmospheric trace gases.Nature reviews. Microbiology · 2022
    Review
  16. Determination of the iron(IV) local spin states of the Q intermediate of soluble methane monooxygenase by Kβ X-ray emission spectroscopy.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
  17. A Copper Cage-Complex as Mimic of the pMMO CuAngewandte Chemie (International ed. in English) · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Richard J JodtsDepartments of Chemistry and Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0001-7467-492X
Matthew O RossDepartments of Chemistry and Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0003-2115-9806
Christopher W KooDepartments of Chemistry and Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, United States.
Peter E DoanDepartments of Chemistry and Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, United States.
Amy C RosenzweigDepartments of Chemistry and Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0001-8472-4134
Brian M HoffmanDepartments of Chemistry and Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-3100-0746
Northwestern University · US

Funding

Metalloenzymes and metal homeostasisR35GM118035 · NIGMS · NORTHWESTERN UNIVERSITY · PI AMY C. ROSENZWEIG · 2016 to 2026
$7.1M
Coboglobins-Cobalt-Substituted Hemoglobins and MyoglobinR01GM111097 · NIGMS · NORTHWESTERN UNIVERSITY · PI HOFFMAN, BRIAN M · 2014 to 2025
$6.7M
Molecular Biophysics Training Program at Northwestern UniversityT32GM008382 · NIGMS · NORTHWESTERN UNIVERSITY · PI RADHAKRISHNAN, ISHWAR · 1990 to 2020
$4.3M
NIGMS NIH HHS R01 GM111097NIGMS NIH HHS R35 GM118035NIGMS NIH HHS T32 GM008382
6 · The paper itself

Abstract

In nature, methane is oxidized to methanol by two enzymes, the iron-dependent soluble methane monooxygenase (sMMO) and the copper-dependent particulate MMO (pMMO). While sMMO's diiron metal active site is spectroscopically and structurally well-characterized, pMMO's copper sites are not. Recent EPR and ENDOR studies have established the presence of two monocopper sites, but the coordination environment of only one has been determined, that within the PmoB subunit and denoted Cu

Indexed as

CopperElectron Spin Resonance SpectroscopyMethylocystaceaeModels, MolecularOxygenasesProtein ConformationCoppermethane monooxygenaseOxygenases

Identifiers

PMID34498465
PMCPMC8811777
OpenAlexW3198577053

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.