Evidence map›Paper›PMID 34498443›Full record

ArticleHaematologica2021

Dose-adjusted EPOCH-rituximab or intensified B-NHL therapy for pediatric primary mediastinal large B-cell lymphoma.

Fabian Knörr, Martin Zimmermann, Andishe Attarbaschi, Edita Kabíčková, Britta Maecker-Kolhoff, Stephanie Ruf, Ingrid Kühnle, Martin Ebinger, Anne-Kathrin Garthe, Ingrid Simonitsch-Klupp and 4 more

Abstract read
In one paragraph

Article in Haematologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Observational
  5. Pediatric lymphomas: overview and diagnostic challenges.Virchows Archiv : an international journal of pathology · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Is Dose-Adjusted EPOCH-R Less Effective in Children Than Adults With Primary Mediastinal B-Cell Lymphoma?Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fabian KnörrUKE, Department of Pediatric Hematology and Oncology, Hamburg.
Martin ZimmermannHannover Medical School, Clinic for Pediatric Hematology and Oncology, Hannover.
Andishe AttarbaschiSt. Anna Children's Hospital, Medical University of Vienna, Department of Pediatric Hematology and Oncology, Vienna.
Edita KabíčkováCharles University and University Hospital Motol, Department of Pediatric Hematology and Oncology, Prague, Czech Republic.
Britta Maecker-KolhoffHannover Medical School, Clinic for Pediatric Hematology and Oncology, Hannover.
Stephanie RufUniversity of Gießen, Pediatric Hematology and Oncology, Gießen.
Ingrid KühnleUniversity Medical Center Göttingen, Division of Pediatric Hematology and Oncology, Göttingen.
Martin EbingerChildren's University Hospital Tübingen, Department of General Pediatrics and Pediatric Hematology/Oncology, Tübingen.
Anne-Kathrin GartheUniversity-Hospital of Münster, Pediatric Hematology and Oncology, Münster.
Ingrid Simonitsch-KluppClinical Institute of Pathology, Medical University of Vienna, Vienna.
Ilske OschliesUniversitätsklinikum Schleswig-Holstein, Campus Kiel, Institute of Pathology, Hematopathology Section and Lymph Node Registry, Kiel.
Wolfram KlapperUniversitätsklinikum Schleswig-Holstein, Campus Kiel, Institute of Pathology, Hematopathology Section and Lymph Node Registry, Kiel.
Birgit BurkhardtUniversity-Hospital of Münster, Pediatric Hematology and Oncology, Münster.
Wilhelm WoessmannUKE, Department of Pediatric Hematology and Oncology, Hamburg. w.woessmann@uke.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lymphoma, B-CellLymphoma, Large B-Cell, DiffuseAntineoplastic Combined Chemotherapy ProtocolsChildCyclophosphamideDoxorubicinEtoposideHumansPrednisoneRituximabVincristineCyclophosphamideDoxorubicinEtoposidePrednisoneRituximabVincristine

Identifiers

PMID34498443
PMCPMC8634171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.