ArticleHaemophilia : the official journal of the World Federation of Hemophilia2021
Shortening the Haemophilia Activities List (HAL) from 42 items to 18 items.
Article in Haemophilia : the official journal of the World Federation of Hemophilia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Psychosocial Outcomes and Quality of Life in Patients with Hemophilia a Without Inhibitors: The HemoLIFE Study.Journal of clinical medicine · 2026Article
- Development of a short form of the Swedish version of the Hemophilia Activities List.Scientific reports · 2025Article
- Acquired haemophilia A in an elderly patient: A case report of functional recovery through physiotherapy.International journal of surgery case reports · 2023Article
- ACTIVLIM-Hemo: A new self-reported, unidimensional and linear measure of activity limitations in persons with haemophilia.Haemophilia : the official journal of the World Federation of Hemophilia · 2023Article
- Validation of the pedHALHaemophilia : the official journal of the World Federation of Hemophilia · 2022Article
- Key considerations to reduce or address respondent burden in patient-reported outcome (PRO) data collection.Nature communications · 2022Review
- Rasch Measurement and Patient Reported Value Claims: A Primer for Hemophilia.Innovations in pharmacy · 2022Article
- Shortening the Haemophilia Activities List (HAL) from 42 items to 18 items.Haemophilia : the official journal of the World Federation of Hemophilia · 2021Article
- Responsiveness and Minimal Important Change of the Haemophilia Activities List in Patients With Inherited Bleeding Disorders.Haemophilia : the official journal of the World Federation of HemophiliaArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe Haemophilia Activities List (HAL) was developed to measure activities and participation in persons with haemophilia (PWH). Shortening the questionnaire may facilitate use of the HAL.
aimThe aim of this study was to determine which items of the HAL are redundant, to construct a shorter version of the HAL, and to determine the construct validity of the HAL
methodsA secondary analysis was performed on pooled data of two published studies using the HAL (seven domains, 42 items, optimum score: 100) in adults with haemophilia A/B. Data were divided into a derivation (62%) and a validation set (38%). Redundant items were identified by evaluation of: floor and ceiling effects, proportions of missing and 'not applicable' responses, inter-item correlations, component loadings in an exploratory factor analysis, internal consistency, and item-total correlations. Correlations with the SF-36 and EQ-5D-5L were used to determine construct validity of the HAL
resultsData on 680 PWH were evaluated. In the derivation dataset (n = 420), median age was 30 years (range 18-80), 43% had severe haemophilia and 61% received prophylaxis. Median (IQR) HAL sum score was 65.0 (55.7-88.8). The stepwise procedure resulted in a HAL
conclusionThis clinimetric study resulted in a >50% shortening of the HAL. The 18-item HAL
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