ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2022
One leg standing time predicts fracture risk in older women independent of clinical risk factors and BMD.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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20 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Diminishing returns of fall reduction for hip fracture prevention in older age.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Pooled it
- Effects of OsteoStrong vs. dynamic multicomponent exercise on physical function in older women in the BONEMORE randomized controlled trial.Aging clinical and experimental research · 2026Trial
- Impact of current and previous smoking on fracture risk in older women: the role of physical function, bone density, and bone microarchitecture.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Gut microbiota associates with frailty in older women.Nature communications · 2026Article
- One-leg standing test in older adults with left-right differences; does dominant foot distinctly decide?BMC musculoskeletal disorders · 2025Article
- Article
- Prediction of hip fracture by high-resolution peripheral quantitative computed tomography in older Swedish women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025Article
- Plantar cutaneous sensation is independently associated with postural balance and lower limb motor function in older adults: the Shizuoka study.European geriatric medicine · 2025Article
- One-Leg Standing Test with Eyes Open as a Screening Tool for Prefrailty in Community-Dwelling Older Japanese Women.Healthcare (Basel, Switzerland) · 2024Article
- High physical activity is associated with greater cortical bone size, better physical function, and with lower risk of incident fractures independently of clinical risk factors in older women from the SUPERB study.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Article
- The role of different physical function tests for the prediction of fracture risk in older women.Journal of cachexia, sarcopenia and muscle · 2024Article
- Type 2 Diabetes and Fracture Risk in Older Women.JAMA network open · 2024Observational
- Radiographic knee osteoarthritis severity has no impact on fall risk: the locomotive syndrome and health outcomes in the aizu cohort study (LOHAS): a cross-sectional study.BMC musculoskeletal disorders · 2024Article
- Geographic variation in bone mineral density and prevalent fractures in the Canadian longitudinal study on aging.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024Article
- Hemoglobin Levels Improve Fracture Risk Prediction in Addition to FRAX Clinical Risk Factors and Bone Mineral Density.The Journal of clinical endocrinology and metabolism · 2023Article
- Diurnal pattern of breaks in sedentary time and the physical function of older adults.Archives of public health = Archives belges de sante publique · 2023Article
- Long term association of hip fractures by questions of physical health in a cohort of men and women.PloS one · 2023Article
- Exercise therapy as a digital therapeutic for chronic disease management: consideration for clinical product development.Frontiers in digital health · 2023Review
- The relationship between cervical proprioception and balance in patients with fibromyalgia syndrome.Rheumatology international · 2022Observational
- The Effects of Er Xian Decoction Combined with Baduanjin Exercise on Bone Mineral Density, Lower Limb Balance Function, and Mental Health in Women with Postmenopausal Osteoporosis: A Randomized Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2022Article
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Authors and funding
12 authors at 6 institutions in 3 countries.
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Abstract
In women of ages 75-80 years, a low one leg standing time (OLST) was associated with an increased risk of incident fractures, independently of bone mineral density and clinical risk factors. OLST contributed substantially to fracture probability, indicating that the test should be considered when evaluating fracture risk in older women.
introductionPhysical function and risk of falls are important risk factors for fracture. A few previous studies have suggested that a one leg standing time (OLST) less than 10 s predicts fracture risk, but the impact of OLST, in addition to known clinical risk factors, for fracture probability is unknown. The aim of this study was to determine the independent contribution of OLST to fracture probability in older women.
methodsThe Sahlgrenska University Hospital Prospective Evaluation of Risk of Bone Fractures (SUPERB) is a prospective population-based study of 3028 women 75-80 years old, recruited from the greater Gothenburg area in Sweden. At baseline, information on risk factors was collected using questionnaires, bone mineral density was measured with dual-energy X-ray absorptiometry (DXA), and OLST was performed.
resultsDuring a median follow-up of 3.6 years (IQR 1.5 years), X-ray-verified incident fractures were identified using health records. OLST was available in 2405 women. OLST less than 10 s was associated with an increased risk for incident hip fracture (Hazard Ratio (HR) 3.02, 95% Confidence Interval (CI) [1.49-6.10]), major osteoporotic fracture (HR 95% CI 1.76 [1.34-1.46]), and nonvertebral fracture (HR 95% CI 1.61 [1.26-2.05]) in Cox regression analyses adjusted for age, height, and weight. Depending on BMD, the 4-year fracture probability increased by a factor of 1.3 to 1.5 in a 75-year-old woman with a low OLST (<10 s).
conclusionA low OLST has a substantial impact on fracture probability and should be considered when evaluating fracture risk in older women.
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