ArticleRadiology. Cardiothoracic imaging2021
Diagnostic and Prognostic Performance of Aortic Valve Calcium Score with Cardiac CT for Aortic Stenosis: A Meta-Analysis.
Article in Radiology. Cardiothoracic imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 21 citations in OpenAlex.
- Review
- Aortic Valve Calcium Score Spectrum Identifies Bimodal Outcomes for Transcatheter Aortic Valve Implantation: Insights From the AMTRAC Registry.Journal of the American Heart Association · 2026Article
- Assessment of Potential Predictors of Aortic Stenosis Severity Using ECG-Gated Multidetector CT in Patients with Bicuspid and Tricuspid Aortic Valves Prior to TAVI.Journal of clinical medicine · 2026Article
- Association of aortic valve size with the degree of aortic valve calcification in severe high-gradient aortic stenosis.European heart journal. Cardiovascular Imaging · 2025Article
- Prognostic and therapeutic implications of a low aortic valve calcium score in patients with low-gradient aortic stenosis.European heart journal. Cardiovascular Imaging · 2025Article
- Current Status of CT Imaging Before Common Transcatheter Interventions for Structural Heart Disease.Diagnostics (Basel, Switzerland) · 2025Review
- Aortic Valve Calcium: A Narrative Review of its Role in the Assessment of Aortic Stenosis and as a Predictor of Post-transcatheter Aortic Valve Implantation Outcomes.Interventional cardiology (London, England) · 2025Review
- Contemporary Multi-modality Imaging of Prosthetic Aortic Valves.Reviews in cardiovascular medicine · 2025Review
- A computer vision model for the identification and scoring of calcium in aortic valve stenosis: a single-center experience.Cardiovascular diagnosis and therapy · 2024Article
- Aortic Valve Calcium Score: Applications in Clinical Practice and Scientific Research-A Narrative Review.Journal of clinical medicine · 2024Review
- Computed tomography imaging in preprocedural planning of transcatheter valvular heart interventions.The international journal of cardiovascular imaging · 2024Review
- Virtual non-contrast series of photon-counting detector computed tomography angiography for aortic valve calcium scoring.The international journal of cardiovascular imaging · 2024Article
- Transcatheter Aortic Valve Replacement Improves Quality of Life and Ventricular Function With Low-Flow/Low-Gradient Aortic Stenosis.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Aortic Valve Calcium Score by Computed Tomography as an Adjunct to Echocardiographic Assessment-A Review of Clinical Utility and Applications.Journal of imaging · 2023Review
- Evaluation of causal heart diseases in cardioembolic stroke by cardiac computed tomography.World journal of radiology · 2023Review
- Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography.Pharmaceuticals (Basel, Switzerland) · 2022Review
- S2 Heart Sound Detects Aortic Valve Calcification Independent of Hemodynamic Changes in Mice.Frontiers in cardiovascular medicine · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the diagnostic and prognostic performance of the aortic valve calcium score (AVCS) with the Agatston method using CT in aortic stenosis (AS) and to assess mean AVCS according to AS severity. MATERIALS AND
methodsIn this meta-analysis, PubMed, Embase, and Cochrane were searched from January 1, 1980, to December 31, 2020, for studies reporting sensitivity and specificity of AVCS using CT for severe AS, mean AVCS in severe and nonsevere AS, and/or hazard ratios for all-cause mortality in AS. Data were pooled using random effect models and meta-analysis software.
resultsTwelve studies (six diagnostic, three prognostic, and 10 reporting mean AVCS by AS severity) were included for analysis. A total of 4101 patients (2255 with severe AS) were described in these 12 studies. Pooled sensitivity and specificity were 82% (95% CI: 80, 84) and 78% (95% CI: 75, 81), respectively. Pooled mean AVCS were 3219 (95% CI: 2795, 3643) for severe AS, compared with 1252 (95% CI: 863, 1640) for nonsevere AS, 1808 (95% CI: 1163, 2452) for moderate AS, and 584 (95% CI: 309, 859) for mild AS. Pooled hazard ratio for AVCS as a binary threshold to predict mortality was 2.11 (95% CI: 1.11, 4.12).
conclusionAVCS had moderate to high sensitivity and specificity for identifying severe AS and was also a useful prognostic imaging marker in AS. Mean AVCS categorized by AS severity may help guide clinical management.
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