Evidence map›Paper›PMID 34498001›Full record

ArticleRadiology. Cardiothoracic imaging2021

The Prognostic Value of Left Ventricular Mechanical Dyssynchrony Derived from Cardiac MRI in Patients with Idiopathic Dilated Cardiomyopathy.

Yangjie Li, Xiumin Liu, Yuanwei Xu, Weihao Li, Siqi Tang, Xiaoyue Zhou, Jiayu Sun, Qing Zhang, Yuchi Han, Yucheng Chen

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PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yangjie LiDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).
Xiumin LiuDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).
Yuanwei XuDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).ORCID 0000-0003-3034-7219
Weihao LiDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).
Siqi TangDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).
Xiaoyue ZhouDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).ORCID 0000-0003-3577-990X
Jiayu SunDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).ORCID 0000-0002-9552-6720
Qing ZhangDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).
Yuchi HanDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).ORCID 0000-0001-7582-1848
Yucheng ChenDepartments of Cardiology (Y.L., Y.X., W.L., S.T., Q.Z., Y.C.) and Radiology (X.L., J.S.), West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu 610041, China; Siemens Healthcare, Shanghai, China (X.Z.); and Cardiovascular Division, Department of Medicine, University of Pennsylvania, Philadelphia, Pa (Y.H.).ORCID 0000-0002-0601-8039

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the prognostic value of mechanical dyssynchrony evaluated by deformable registration algorithm (DRA) analysis of cardiac MRI (CMR) in patients with idiopathic dilated cardiomyopathy (DCM). MATERIALS AND

methodsThis secondary analysis of a prospective study (clinical trial no. ChiCTR1800017058) enrolled 409 patients (mean age, 48 years ± 14:300 men) with idiopathic DCM who underwent CMR between June 2012 and September 2018. Mechanical dyssynchrony was measured as standard deviation of time-to-peak (sdTTP) and uniformity ratio estimate (URE) indexes by DRA strain analysis. The primary endpoint included all-cause mortality and heart transplantation. The secondary endpoint included primary endpoint, aborted sudden cardiac death, and heart failure readmission. Cox regression analyses and Kaplan-Meier survival analysis were performed to identify the association between variables and outcomes.

resultsDuring a median follow-up of 25.1 months, 57 and 132 patients reached primary and secondary endpoints, respectively. Most URE indexes were significantly lower in patients reaching primary endpoint. In multivariable analysis, circumferential URE (CURE) at apical level was independently associated with primary endpoints (hazard ratio, 0.307 [95% CI: 0.106, 0.883];

conclusionURE indexes were more predictive of prognostic outcomes compared with sdTTP measurements; the CURE at apical level was an independent predictor of adverse cardiac events in patients with DCM.

Indexed as

HeartMR-ImagingOutcomes Analysis

Identifiers

PMID34498001
PMCPMC8415147

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.