Evidence map›Paper›PMID 34497676›Full record

ReviewDisease markers2021

Signal Pathways and Markers Involved in Acute Lung Injury Induced by Acute Pancreatitis.

Jialin Zhou, Pengcheng Zhou, Yingyi Zhang, Guangzhi Wang, Zhe Fan

Open access · hybridAbstract readReview
In one paragraph

Review in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Genetic and pharmacologic modulations elucidate NRF2 protective role in acute pancreatitis.American journal of physiology. Gastrointestinal and liver physiology · 2026
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  11. Role of Sphingosine-1-Phosphate Signaling Pathway in Pancreatic Diseases.International journal of molecular sciences · 2024
    Review
  12. Review
  13. Heart rate variability in acute pancreatitis: a narrative review.Translational gastroenterology and hepatology · 2024
    Review
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jialin ZhouDepartment of General Surgery, The Third People's Hospital of Dalian, Dalian Medical University, Dalian, China.
Pengcheng ZhouSchool of Medicine, Southeast University, Nanjing, China.
Yingyi ZhangDepartment of General Surgery, The Third People's Hospital of Dalian, Dalian Medical University, Dalian, China.ORCID https://orcid.org/0000-0002-5075-8341
Guangzhi WangDepartment of General Surgery, The Second Hospital of Dalian Medical University, Dalian, China.ORCID https://orcid.org/0000-0001-8731-1976
Zhe FanDepartment of General Surgery, The Third People's Hospital of Dalian, Dalian Medical University, Dalian, China.ORCID https://orcid.org/0000-0002-2446-1122
Dalian Medical University · CNSoutheast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pancreatitis (AP) is a common acute abdominal disease with a mortality rate of about 30%. Acute lung injury (ALI) is a common systemic complication of acute pancreatitis, with progressive hypoxemia and respiratory distress as the main manifestations, which can develop into acute respiratory distress syndrome or even multiple organ dysfunction syndrome (MODS) in severe cases, endangering human health. In the model of AP, pathophysiological process of the lung can be summarized as oxidative stress injury, inflammatory factor infiltration, and alveolar cell apoptosis. However, the intrinsic mechanisms underlying AP and how it leads to ALI are not fully understood. In this paper, we summarize recent articles related to AP leading to ALI, including the signal transduction pathways and biomarkers of AP-ALI. There are factors or pathway aggravating ALI, the JAK2-STAT3 signaling pathway, NLRP3/NF-

Indexed as

Acute Lung InjuryBiomarkersHumansPancreatitisSignal TransductionBiomarkers

Identifiers

PMID34497676
PMCPMC8419500
OpenAlexW3197086784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.