Evidence map›Paper›PMID 34497663›Full record

ArticleComputational and mathematical methods in medicine2021

Establishment of an Immune-Related Gene Signature for Risk Stratification for Patients with Glioma.

Jimin He, Chun Zeng, Yong Long

Open access · hybridAbstract readValidation Study
In one paragraph

Article in Computational and mathematical methods in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jimin HeDepartment of Neurosurgery, Suining Central Hospital, Suining, China.ORCID https://orcid.org/0000-0002-7494-494X
Chun ZengDepartment of Neurosurgery, Suining Central Hospital, Suining, China.ORCID https://orcid.org/0000-0001-8670-1630
Yong LongDepartment of Neurosurgery, Suining Central Hospital, Suining, China.ORCID https://orcid.org/0000-0003-1371-614X
Suizhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma is a frequently seen primary malignant intracranial tumor, characterized by poor prognosis. The study is aimed at constructing a prognostic model for risk stratification in patients suffering from glioma. Weighted gene coexpression network analysis (WGCNA), integrated transcriptome analysis, and combining immune-related genes (IRGs) were used to identify core differentially expressed IRGs (DE IRGs). Subsequently, univariate and multivariate Cox regression analyses were utilized to establish an immune-related risk score (IRRS) model for risk stratification for glioma patients. Furthermore, a nomogram was developed for predicting glioma patients' overall survival (OS). The turquoise module (cor = 0.67;

Indexed as

Biomarkers, TumorBrain NeoplasmsComputational BiologyGene Expression ProfilingGene Expression Regulation, NeoplasticGene Regulatory NetworksGliomaHumansImmunotherapyNomogramsPrognosisProportional Hazards ModelsProtein Interaction MapsRisk FactorsBiomarkers, Tumor

Identifiers

PMID34497663
PMCPMC8420975
OpenAlexW3197953113

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.