Evidence map›Paper›PMID 34497586›Full record

ArticleFrontiers in endocrinology2021

Development and Validation of a Clinical Pregnancy Failure Prediction Model for Poor Ovarian Responders During IVF/ICSI.

Fangyuan Li, Ruihui Lu, Cheng Zeng, Xin Li, Qing Xue

Open access · goldAbstract readValidation Study
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. TransrectalFrontiers in medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fangyuan LiDepartment of Gynecology and Obstetrics, Peking University First Hospital, Beijing, China.
Ruihui LuDepartment of Gynecology and Obstetrics, Peking University First Hospital, Beijing, China.
Cheng ZengDepartment of Gynecology and Obstetrics, Peking University First Hospital, Beijing, China.
Xin LiDepartment of Gynecology and Obstetrics, Peking University First Hospital, Beijing, China.
Qing XueDepartment of Gynecology and Obstetrics, Peking University First Hospital, Beijing, China.
Peking University · CNPeking University First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backgrounds: Despite the great advances in assisted reproductive technology (ART), poor ovarian response (POR) is still one of the most challenging tasks in reproductive medicine. This predictive model we developed aims to predict the individual probability of clinical pregnancy failure for poor ovarian responders (PORs) under Methods: The nomogram was developed in 281 patients with POR according to the Bologna criteria from January 2016 to December 2019, with 179 in the training group and 102 in the validation group. Univariate and multivariate logistic regression analyses were used to identify characteristics that were associated with clinical pregnancy failure. The nomogram was constructed based on regression coefficients. Performance was evaluated using both calibration and discrimination. Results: Age >35 years, body mass index (BMI) >24 kg/m Conclusion: Our nomogram can predict the probability of clinical pregnancy failure in PORs before embryo transfer in IVF/ICSI procedure, to help practitioners make appropriate clinical decisions and to help infertile couples manage their expectations.

Indexed as

NomogramsReproductive Techniques, AssistedAdultChorionic GonadotropinEmbryo TransferEstrogensFemaleFertilization in VitroFollicle Stimulating HormoneFollow-Up StudiesHumansInfertility, FemaleOvaryOvulation InductionPregnancyPregnancy OutcomeChorionic GonadotropinEstrogensFollicle Stimulating Hormoneclinical pregnancy failureIVF/ICSInomogrampoor ovarian responsepredictive model

Identifiers

PMID34497586
PMCPMC8419272
OpenAlexW3194030833

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.