Evidence map›Paper›PMID 34497520›Full record

ArticleFrontiers in pharmacology2021

Effects of Naringin on Cardiomyocytes From a Rodent Model of Type 2 Diabetes.

A Uryash, A Mijares, V Flores, J A Adams, J R Lopez

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. [Melatonin alleviates cardiomyocyte necroptosis in diabetic mice by inhibiting the STING signaling pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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  18. The Role of the NaFrontiers in cellular and infection microbiology · 2022
    Article
  19. Chronic Elevation of Skeletal Muscle [CaFrontiers in physiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

A UryashDepartment of Neonatology, Mount Sinai Medical Center, Miami, FL, United States.
A MijaresCentro de Biofísica y Bioquímica, Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela.
V FloresDepartment of Research, Mount Sinai Medical Center, Miami, FL, United States.
J A AdamsDepartment of Neonatology, Mount Sinai Medical Center, Miami, FL, United States.
J R LopezDepartment of Research, Mount Sinai Medical Center, Miami, FL, United States.
Mount Sinai Medical Center · USInstituto Venezolano de Investigaciones Científicas · VE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic cardiomyopathy (DCM) is a primary disease in diabetic patients characterized by diastolic dysfunction leading to heart failure and death. Unfortunately, even tight glycemic control has not been effective in its prevention. We have found aberrant diastolic Ca

Indexed as

calciumcardiomyopathydiabetesglibenclamideKATP channelsnaringinnicorandilROS

Identifiers

PMID34497520
PMCPMC8419284
OpenAlexW3194153378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.