Evidence map›Paper›PMID 34497423›Full record

ArticleNature2021

The EDS1-PAD4-ADR1 node mediates Arabidopsis pattern-triggered immunity.

Rory N Pruitt, Federica Locci, Friederike Wanke, Lisha Zhang, Svenja C Saile, Anna Joe, Darya Karelina, Chenlei Hua, Katja Fröhlich, Wei-Lin Wan and 16 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 205 papers.

0numbers the graph read from it
0cells of the map it votes in
205citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

205 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Mechanisms and balanced regulation of plant immunity.Nature reviews. Molecular cell biology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Diversification and deployment of PRR and NLR immune receptors in potato.The Plant journal : for cell and molecular biology · 2026
    Review
  13. Article
  14. Article
  15. Review
  16. Genome-Wide Identification and Expression Analysis of theCurrent issues in molecular biology · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Review

145 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Rory N Pruitt *Department of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-4134-8156
Federica Locci *Department of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.ORCID http://orcid.org/0000-0001-5443-0717
Friederike WankeDepartment of Plant Physiology, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0001-6080-8800
Lisha ZhangDepartment of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-8203-2369
Svenja C SaileDepartment of Plant Physiology, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0003-2258-3166
Anna JoeDepartment of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.
Darya KarelinaDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, Tübingen, Germany.
Chenlei HuaDepartment of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.
Katja FröhlichDepartment of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-9491-5927
Wei-Lin WanDepartment of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.
Meijuan HuState Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing, China.
Shaofei RaoState Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing, China.
Sara C StolzeProteomics Group, Max Planck Institute for Plant Breeding Research, Cologne, Germany.ORCID http://orcid.org/0000-0002-1421-9703
Anne HarzenProteomics Group, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Andrea A GustDepartment of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0003-0466-2792
Klaus HarterDepartment of Plant Physiology, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.
Matthieu H A J JoostenLaboratory of Phytopathology, Wageningen University, Wageningen, Netherlands.
Bart P H J ThommaLaboratory of Phytopathology, Wageningen University, Wageningen, Netherlands.ORCID http://orcid.org/0000-0003-4125-4181
Jian-Min ZhouState Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Innovation Academy for Seed Design, Chinese Academy of Sciences, Beijing, China.ORCID http://orcid.org/0000-0002-9943-2975
Jeffery L DanglDepartment of Biology, Howard Hughes Medical Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-3199-8654
Detlef WeigelDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, Tübingen, Germany.
Hirofumi NakagamiProteomics Group, Max Planck Institute for Plant Breeding Research, Cologne, Germany.ORCID http://orcid.org/0000-0003-2569-7062
Claudia OeckingDepartment of Plant Physiology, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.
Farid El KasmiDepartment of Plant Physiology, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-4634-7689
Jane E ParkerDepartment of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany. parker@mpipz.mpg.de.ORCID http://orcid.org/0000-0002-4700-6480
Thorsten NürnbergerDepartment of Plant Biochemistry, Centre of Plant Molecular Biology (ZMBP), University of Tübingen, Tübingen, Germany. nuernberger@uni-tuebingen.de.ORCID http://orcid.org/0000-0002-7804-7170

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants deploy cell-surface and intracellular leucine rich-repeat domain (LRR) immune receptors to detect pathogens

Indexed as

Plant ImmunityArabidopsisArabidopsis ProteinsCarboxylic Ester HydrolasesDNA-Binding ProteinsProtein DomainsProtein KinasesProtein MultimerizationProtein Serine-Threonine KinasesReceptors, Cell SurfaceADR1 protein, ArabidopsisArabidopsis ProteinsAT1G76360 protein, ArabidopsisAT4G35600 protein, ArabidopsisCarboxylic Ester HydrolasesDNA-Binding ProteinsEDS1 protein, ArabidopsisPAD4 protein, ArabidopsisProtein KinasesProtein Serine-Threonine KinasesReceptors, Cell SurfaceRLP23 protein, ArabidopsisSOBIR protein, Arabidopsis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.