ArticleScientific reports2021
Individual alpha peak frequency is slower in schizophrenia and related to deficits in visual perception and cognition.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 87 citations in OpenAlex.
- Relationship between Habitual Caffeine Consumption, Attentional Performance, and Individual Alpha Frequency during Total Sleep Deprivation.International journal of environmental research and public health · 2023Trial
- Understanding Attention in Schizophrenia: The Enduring Influence of Barbara Cornblatt.Schizophrenia bulletin · 2026Review
- Predictive Inference Alterations in Psychosis Proneness Show Task-Dependent Signatures.Annals of the New York Academy of Sciences · 2026Article
- Quantitative Electroencephalography as a Complement to Symptom-Based Psychiatric Diagnosis: A Narrative Review.Journal of personalized medicine · 2026Review
- Alpha frequency shapes perceptual sensitivity by modulating optimal phase likelihood.Nature communications · 2026Article
- A human electrophysiological signature of Fragile X pathophysiology is shared in V1 of Fmr1Nature communications · 2026Article
- Parietal alpha frequency shapes own-body perception by modulating the temporal integration of bodily signals.Nature communications · 2026Article
- Quantitative electroencephalography as a potential neurophysiological diagnostic biomarker of schizophrenia and first-episode psychosis: a systematic review of clinical implications.Frontiers in psychiatry · 2026Review
- Dynamics of thoughts-novel candidate marker for differential-diagnosis of mental disorders?Journal of psychiatry & neuroscience : JPN · 2026Review
- Mapping EEG Metrics to Human Affective and Cognitive Models: An Interdisciplinary Scoping Review from a Cognitive Neuroscience Perspective.Biomimetics (Basel, Switzerland) · 2025Review
- Periodic and Aperiodic Alterations of Resting-State EEG in Schizophrenia Spectrum Disorders: Cognitive and Clinical Insights.The European journal of neuroscience · 2025Article
- Individual alpha frequency tACS modifies the detection of space-time optical illusion.Experimental brain research · 2025Article
- Large-scale maps of altered cortical dynamics in early-stage psychosis are related to GABAergic and glutamatergic neurotransmission.Science advances · 2025Article
- Temporal acuity of vision decreases with eccentricity in virtual reality and is associated with schizotypy.Scientific reports · 2025Article
- Generalized Slowing of Resting-State Neural Oscillations in People With Schizophrenia.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Delusion-like thinking is associated with lower individual alpha peak frequency.Schizophrenia (Heidelberg, Germany) · 2025Article
- Peak alpha frequency as an objective biomarker for cognitive assessment in post-stroke cognitive impairment.Frontiers in aging neuroscience · 2025Article
- Altered Use of Context During Visual Perception in Psychotic Psychopathology: A Neurophysiological Investigation of Tuned and Untuned Suppression During Contrast Perception.Schizophrenia bulletin · 2024Article
- Peak Alpha Frequency in Schizophrenia, Bipolar Disorder, and Healthy Volunteers: Associations With Visual Information Processing and Cognition.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Electroencephalographic Microstates During Sleep and Wake in Schizophrenia.Biological psychiatry global open science · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The brain at rest generates cycles of electrical activity that have been shown to be abnormal in people with schizophrenia. The alpha rhythm (~ 10 Hz) is the dominant resting state electrical cycle and each person has a propensity toward a particular frequency of oscillation for this rhythm. This individual alpha peak frequency (IAPF) is hypothesized to be central to visual perceptual processes and may have downstream influences on cognitive functions such as attention, working memory, or problem solving. In the current study we sought to determine whether IAPF was slower in schizophrenia, and whether lower IAPF predicted deficits in visual perception and cognition that are often observed in schizophrenia. Eyes-closed resting state EEG activity, visual attention, and global cognitive functioning were assessed in individuals with schizophrenia (N = 104) and a group of healthy controls (N = 101). Compared to controls, the schizophrenia group showed slower IAPF and was associated with poorer discrimination of visual targets and nontargets on a computerized attention task, as well as impaired global cognition measured using neuropsychological tests across groups. Notably, disruptions in visual attention fully mediated the relationship between IAPF and global cognition across groups. The current findings demonstrate that slower alpha oscillatory cycling accounts for global cognitive deficits in schizophrenia by way of impairments in perceptual discrimination measured during a visual attention task.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.