ArticleScientific reports2021
Retinal blood flow reversal quantitatively monitored in out-of-plane vessels with laser Doppler holography.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Laser doppler holography for choroidal blood flow assessment: a systematic review of technical capabilities, validation studies, and clinical applications.Frontiers in ophthalmology · 2026Pooled it
- The Organization of Choroidal Arteries in Normal Eyes.Ophthalmology science · 2026Article
- Repeatability and reliability of retinal arterial hemodynamics measurement using Doppler holography.Journal of biomedical optics · 2026Article
- Blood flow analysis of retinal neovascularisations in a VLDLR mouse model using contrast-enhanced optical coherence tomography.Biomedical optics express · 2026Article
- Interaction Between Glaucoma and Central Retinal Vein Occlusion in a Cohort Study.Journal of clinical medicine · 2025Article
- Visual stimulus-evoked transient blood flow and blood vessel diameter changes in the healthy human retina measured with a combined OCT+ERG system.Biomedical optics express · 2025Article
- Evaluating Blood Flow Speed in Retinal Microaneurysms Secondary to Diabetic Retinopathy Using Variable Interscan Time Analysis OCTA.Translational vision science & technology · 2025Article
- Large-scale super-resolution optoacoustic imaging facilitated by FeNP/ICG-loaded coreless polyelectrolyte microcapsules.Theranostics · 2025Article
- Plexus-Specific Retinal Capillary Blood Flow Analysis Using Erythrocyte Mediated Angiography and Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2024Article
- Quantitative study of spatial and temporal variation in retinal capillary network perfusion in rat eye by in vivo confocal imaging.Scientific reports · 2023Article
- Super-Resolution Ultrasound Localization Microscopy Using High-Frequency Ultrasound to Measure Ocular Perfusion Velocity in the Rat Eye.Bioengineering (Basel, Switzerland) · 2023Article
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Authors and funding
3 authors.
Funding
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Abstract
Laser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology to image human retinal and choroidal blood flow non-invasively. Here we present a digital method based on the Doppler spectrum asymmetry that reveals the local direction of blood flow with respect to the optical axis in out-of-plane vessels. This directional information is overlaid on standard grayscale blood flow images to depict flow moving towards the camera in red and flow moving away from the camera in blue, as in ultrasound color Doppler imaging. We show that thanks to the strong contribution of backscattering to the Doppler spectrum in out-of-plane vessels, the local axial direction of blood flow can be revealed with a high temporal resolution, which enables us to evidence pathological blood flow reversals. We also demonstrate the use of optical Doppler spectrograms to quantitatively monitor retinal blood flow reversals.
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