Evidence map›Paper›PMID 34497091›Full record

ArticleBMJ (Clinical research ed.)2021

Residential exposure to transportation noise in Denmark and incidence of dementia: national cohort study.

Manuella Lech Cantuaria, Frans Boch Waldorff, Lene Wermuth, Ellen Raben Pedersen, Aslak Harbo Poulsen, Jesse Daniel Thacher, Ole Raaschou-Nielsen, Matthias Ketzel, Jibran Khan, Victor H Valencia and 2 more

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. [Modifiable risk and protective factors for dementia: an overview of established and emerging evidence].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
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  13. Social determinants of dementia: A scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Noise and mental health: evidence, mechanisms, and consequences.Journal of exposure science & environmental epidemiology · 2025
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Manuella Lech CantuariaThe Mærsk McKinney Møller Institute, University of Southern Denmark, Odense, Denmark mlca@mmmi.sdu.dk.ORCID 0000-0003-3201-9606
Frans Boch WaldorffDepartment of Public Health, The Research Unit for General Practice and Section of General Practice, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-7859-633X
Lene WermuthDepartment of Neurology, Slagelse Hospital, Slagelse, Denmark.ORCID 0000-0001-6930-8562
Ellen Raben PedersenThe Mærsk McKinney Møller Institute, University of Southern Denmark, Odense, Denmark.ORCID 0000-0001-9917-9837
Aslak Harbo PoulsenDiet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark.ORCID 0000-0003-4456-4169
Jesse Daniel ThacherDiet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark.ORCID 0000-0003-4908-9715
Ole Raaschou-NielsenDiet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark.ORCID 0000-0002-1223-0909
Matthias KetzelDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.ORCID 0000-0001-9519-1935
Jibran KhanDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.ORCID 0000-0003-2080-2871
Victor H ValenciaDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.ORCID 0000-0001-8211-6776
Jesper Hvass SchmidtResearch Unit for ORL - Head and Neck Surgery and Audiology, Odense University Hospital, Odense, Denmark.ORCID 0000-0001-7683-1407
Mette SørensenDiet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark.ORCID 0000-0002-7302-4789

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the association between long term residential exposure to road traffic and railway noise and risk of incident dementia.

designNationwide prospective register based cohort study.

settingDenmark.

participants1 938 994 adults aged ≥60 years living in Denmark between 1 January 2004 and 31 December 2017.

main outcome measuresIncident cases of all cause dementia and dementia subtypes (Alzheimer's disease, vascular dementia, and Parkinson's disease related dementia), identified from national hospital and prescription registries.

resultsThe study population included 103 500 participants with incident dementia, and of those, 31 219 received a diagnosis of Alzheimer's disease, 8664 of vascular dementia, and 2192 of Parkinson's disease related dementia. Using Cox regression models, 10 year mean exposure to road traffic and railway noise at the most (L

conclusionsThis nationwide cohort study found transportation noise to be associated with a higher risk of all cause dementia and dementia subtypes, especially Alzheimer's disease.

Indexed as

AgedCausalityDementiaDenmarkFemaleHumansIncidenceMaleMiddle AgedNoise, TransportationProportional Hazards ModelsProspective StudiesRegistries

Identifiers

PMID34497091
PMCPMC8424489

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.