Evidence map›Paper›PMID 34497070›Full record

ArticleRNA (New York, N.Y.)2021

Stress-induced inhibition of mRNA export triggers RNase III-mediated decay of the

Charles Wang, Keaton Barr, Dean Neutel, Kevin Roy, Yanru Liu, Guillaume F Chanfreau

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Transcription termination promotes splicing efficiency and fidelity in a compact genome.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Charles WangDepartment of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, USA.
Keaton BarrDepartment of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, USA.
Dean NeutelDepartment of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, USA.
Kevin RoyDepartment of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, USA.
Yanru LiuDepartment of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, USA.
Guillaume F ChanfreauDepartment of Chemistry and Biochemistry, UCLA, Los Angeles, California 90095, USA.
University of California, Los Angeles · US

Funding

UCLA NIGMS T32 Program AssessmentT32GM007185 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TORRES, JORGE · 1985 to 2020
$21.7M
UCLA MSD ProgramR25GM055052 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BARBER, PAUL HENRY, HASSON, TAMA W. · 1996 to 2021
$9.2M
The Control of Gene Expression by Eukaryotic RibonucleasesR35GM130370 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Guillaume F Chanfreau · 2019 to 2026
$3.3M
NIGMS NIH HHS R25 GM055052NIGMS NIH HHS R35 GM130370NIGMS NIH HHS T32 GM007185
6 · The paper itself

Abstract

The expression of bromodomain-containing proteins that regulate chromatin structure and accessibility must be tightly controlled to ensure the appropriate regulation of gene expression. In the yeast

Indexed as

RNA TransportSalt StressActive Transport, Cell NucleusBromodomain Containing ProteinsCell NucleusRibonuclease IIIRNA, MessengerSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsBDF2 protein, S cerevisiaeBromodomain Containing ProteinsRibonuclease IIIRNA, MessengerSaccharomyces cerevisiae ProteinsTranscription FactorsBromodomainmRNA exportRNase IIIRnt1pstress

Identifiers

PMID34497070
PMCPMC8594472
OpenAlexW3197763684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.