Evidence map›Paper›PMID 34496916›Full record

SynthesisWorld journal of emergency surgery : WJES2021

Subtotal cholecystectomy for difficult acute cholecystitis: how to finalize safely by laparoscopy-a systematic review.

Adriana Toro, Michele Teodoro, Mansoor Khan, Elena Schembari, Salomone Di Saverio, Fausto Catena, Isidoro Di Carlo

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in World journal of emergency surgery : WJES, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  7. Acute cholecystitis: a new technique to use carefully.World journal of emergency surgery : WJES · 2025
    Article
  8. Laparoscopic Subtotal Cholecystectomy for Difficult Gallbladders: Single-Center Retrospective Cohort Study.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2025
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  17. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Adriana ToroGeneral Surgery, Augusta Hospital, Siracusa, Italy.
Michele TeodoroDepartment of Emergency, S. Marco Hospital, Catania, Italy.
Mansoor KhanBrighton and Sussex University Hospitals NHS Trust, Brighton, UK.
Elena SchembariDepartment of General Surgery, Whipps Cross University Hospital-Barts Health NHS Trust, London, UK.
Salomone Di SaverioGeneral Surgery, University of Insubria, Varese, Italy.
Fausto CatenaEmergency and Trauma Surgery, Parma Maggiore Hospital, Parma, Italy.
Isidoro Di CarloDepartment of Surgical Sciences and Advanced Technologies "G.F. Ingrassia", Cannizzaro Hospital, University of Catania, Via Messina 829, 95126, Catania, Italy. idicarlo@unict.it.
Ospedale di Parma · ITUniversity Hospitals Sussex NHS Foundation Trust · GBUniversity of Catania · ITUniversity of Insubria · ITWhipps Cross University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAim of this study was to clarify the best laparoscopic subtotal cholecystectomy (LSTC) technique for finalizing a difficult cholecystectomy. PATIENTS AND

methodsA review was performed (1987-2021) searching "difficulty cholecystectomy" AND/OR "subtotal cholecystectomy". The LSTC techniques considered were as follows: type A, leaving posterior wall attached to the liver and the remainder of the gallbladder stump open; type B, like type A but with the stump closed; type C, resection of both the anterior and posterior gallbladder walls and the stump closed; type D, like type C but with the stump open. Morbidity (including mortality) was analysed with Dindo-Clavien classification.

resultsNineteen articles were included. Of the 13,340 patients screened, 678 (8.2%) had cholecystectomy finalized by LSTC: 346 patients (51.0%) had type A LSTC, 134 patients (19.8%) had type B LSTC, 198 patients (29.2%) had type C LSTC, and 198 patients (0%) had type D LSTC. Bile leakage was found in 83 patients (12.2%), and recorded in 58 patients (69.9%) treated by type A. Twenty-three patients (3.4%) developed a subhepatic collection, 19 of whom (82.6%) were treated by type A. Other complications were reported in 72 patients (10.6%). The Dindo-Clavien classification was four for grade I, 27 for grade II, 126 for grade IIIa, 18 for grade IIIb, zero for grade IV and three for grade V.

conclusionIn the case of LSTC, closure of the gallbladder stump represents the best method to avoid complications. Careful exploration of the gallbladder stump is mandatory, washing the abdominal cavity and leaving drainage.

Indexed as

CholecystectomyCholecystectomy, LaparoscopicCholecystitis, AcuteHumansClavien–Dindo classificationComplicationsDifficulty cholecystectomyGallbladderLaparoscopic subtotal cholecystectomy

Identifiers

PMID34496916
PMCPMC8424983
OpenAlexW3196506823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.